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CREB
ACTH4
Histone H3K9me3 (1
VU6007496 2127101
Preclinical evaluation of a novel antibody
Neuregulin
血红素结合蛋白 2(HEBP2)基因
Schisandrin B inhibits epithelial‑mesenchymal transition and stemness of large‑cell lung cancer cells and tumorigenesis in xenografts via inhibiting the NF‑κB and p38 MAPK signaling pathways PMID 33907830
Grp75/MOT 抗体 (YA3155)(Grp75/MOT Antibody (YA3155))
5
Emodin inhibits respiratory syncytial virus entry by interactions with fusion protein PMID 38817970
铁死亡:癌症治疗及其他领域的关键调控机制
Metabolism of 25
Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3
IXA4 1185329
Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling PMID 26500555
Stomach encyclopedia Combined single
Block of the hERG channel by bupivacaine Electrophysiological and modeling insights towards stereochemical optimization PMID 21624711
Dihydroquercetin improves the proliferation of porcine intestinal epithelial cells via the Wnt/β
Sulfated sulfakinin
12(S)
Fenbutatin oxide 13356
Modulating tumor
Epolactaene 167782
Discovery of novel 4
The β
Flonicamid, a novel insecticide with a rapid inhibitory effect on aphid feeding PMID 17659536
Design, synthesis and molecular modeling of pyrazole
Mitochondrial Metabolism
GSK2837808A 1445879
Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis Therapeutic Implications for Alzheimer's Disease PMID 30758770
Dexmedetomidine Attenuates Hypoxia/Reoxygenation Injury of H9C2 Myocardial Cells by Upregulating miR
Lipocalin
Calcium/Calmodulin
Poldip2 knockdown protects against lipopolysaccharide
The UBA1
Shikonin potentiates therapeutic efficacy of oxaliplatin through reactive oxygen species
Urolithin A Attenuates Periodontitis in Mice via Dual Anti
In vivo and in vitro study on the regulatory mechanism of XiaoChaiHu decoction on PANoptosis in sepsis
5
Curcumol Enhances the Sensitivity of Gastric Cancer to Cisplatin Resistance by Inducing Ferroptosis Through the P62/KEAP1/NRF2 Pathway PMID 39511708
Structures and activity of angiotensin
Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation PMID 32855239
Multifunctional Hydrogel Eye Drops for Synergistic Treatment of Ocular Inflammatory Disease PMID 37890030
CI
EV71
Potent reversible inhibitors of the protein tyrosine phosphatase CD45 PMID 11356112
PF 1022A
Amlodipine
N
CRIPT
CHNQD
L
Acepromazine
SGCE promotes breast cancer stemness by promoting the transcription of FGF
Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety Synthesis, mRNA Modification, and Translation for Therapeutic Applications PMID 34008991
MC3343
2
Amylin structure
The selectivity of beta
Secretin (swine) 17034
Effects of the novel endocannabinoid uptake inhibitor, LY2183240, on fear
Ipratropium bromide
Glycocitrine I 82354
Evaluation of Genotoxic Effects of N
Quinaprilat
JMJD3 Promotes Porphyromonas gingivalis Lipopolysaccharide
The hedgehog and Wnt/β
Nitroxoline induces cell apoptosis by inducing MDM2 degradation in small
12
Design of gp120 HIV
Pharmacokinetics and Biodistribution of Aurantiamide and Aurantiamide Acetate in Rats after Oral Administration of Portulaca oleracea L. Extracts PMID 27075043
Rhodomyrtone 468757
MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade PMID 35017531
Bioinspired β
The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma PMID 21980408
Development of a Potent Nurr1 Agonist Tool for In Vivo Applications PMID 37127285
CHFR promotes metastasis of human gastric carcinoma by activating AKT and ERK via NRF2
The Effect of Cuproptosis
Antifungal agent 21 1622299
GSK
DC
PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL
Excessive load promotes temporomandibular joint chondrocyte apoptosis via Piezo1/endoplasmic reticulum stress pathway PMID 38842129
Benzyl
Dynorphin A (1
Effect of Casein Hydrolysate on Cardiovascular Risk Factors A Systematic Review and Meta
18 2 Lyso PA sodium
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα PMID 30314280
Mitoxantrone diacetate 70711
Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. II. Structure elucidation of terpendoles A, B, C and D PMID 7868389
KRP
Duhuo jisheng decoction alleviates osteoarthritis progression by mitigating ferroptosis in chondrocytes via the nuclear factor erythroid 2
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells PMID 36947320
Basigin/CD147 蛋白, Mouse (HEK293, His
Combination of oral STING agonist MSA
The mechanism of inhibitory action of diltiazem on vascular smooth muscle contractility PMID 7252845
Stress susceptibility in pigs supplemented with ractopamine PMID 23825348
4
Biotin
Age
The main protease of SARS
Molecular insights on PS
(±)
Proof
Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS
Inhibition by oxonic acid of gastrointestinal toxicity of 5
Banxia Xiexin Tang attenuates high glucose
Effect of protease and cellulase on the characteristic of activated sludge PMID 20138701
Kallikrein
N
SOX2 suppresses osteoblast differentiation of MC3T3
Diethylstilbestrol (DES)
Role of phospholipase A₂ (PLA₂) inhibitors in attenuating apoptosis of the corneal epithelial cells and mitigation of Acanthamoeba keratitis PMID 23792108
Rps6ka4 Rat Pre
Monohexyl phthalate 24539
Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer PMID 36131027
1
Novel dithiocarbamates selectively inhibit 3CL protease of SARS
Cilnidipine
Plerixafor stimulates adhesive activity and endothelial regeneration of endothelial progenitor cells via elevating CXCR7 expression PMID 32741660
Fumaryl
Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF
MK
Incorporation of a chiral gem
EPHB6
SPI1
KPT
Suppression of NFAT5
Effect of long
Evaluation of pharmacokinetics, brain levels and protein binding of centpropazine in rats PMID 14872554
Cancer
Genotype differences in susceptibility and resistance development of hepatitis C virus to protease inhibitors telaprevir (VX
F11r
Sodium 3
N
Azido
Ginkgolide B promotes the proliferation and differentiation of neural stem cells following cerebral ischemia/reperfusion injury, both in vivo and in vitro PMID 30028328
Small molecules CK
Nitazoxanide
(4aS,8aR)
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV
Two novel phenanthraquinones with anti
(
Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA PMID 36195598
Rucaparib tartrate 773059
Characterisation of the PTEN inhibitor VO
Targeted degradation of GOLM1 by CC
DDO
Discovery of a potent inhibitor targeting the cap
Methyl 9(S),10(R)
MCE
Crystal Structures of mPGES
Gastrin 抗体 (YA5685)(Gastrin Antibody (YA5685))
Guanosine 5'
Menotropin 61489
Design, synthesis, mechanistic and histopathological studies of small
Secondary Metabolites from the Endophytic Fungus Letendraea helminthicola A820 with Anti
Winrevair
Thieno[2,3
Berninamycin A
Inhibition of NEK2 Promotes Chemosensitivity and Reduces KSHV
TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K
Antagonizing effects of curcumin against mercury
4
WDFY4 Promotes the Progression of Atherosclerosis by Regulating Ferroptosis Mediated by the LAPTM5/CDC42/mTOR/4EBP1/SLC7A11 Pathway PMID 40755163
Acetazolamide Serves as Selective Delivery Vehicle for Dipeptide
DD
Geniposide protects depression through BTK/JAK2/STAT1 signaling pathway in lipopolysaccharide
Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent PMID 30346772
m
Xylohexaose (木六糖)
Pimonidazole hydrochloride 70132
Involvement of sphingosine
MOF
Paeoniflorin alleviates high glucose
SNC86
Anetumab 1954758
LINC00858 facilitates formation of hepatic metastases from colorectal cancer via regulating the miR
WNT 信号通路的 MCC 调节因子(MCC)基因
Telcagepant
Benzyl 2
Development of human lactate dehydrogenase a inhibitors high
A novel complement C1q A chain from marbled flounder, Pseudopleuronectes yokohamae genome characterization, expression and potential role in antibacterial immunity PMID 40349809
Suppression of Prostate Cancer Pathogenesis Using an MDA
Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction
Protective effects of 4
N6
SB
Furegrelate sodium 85666
hepatocellular
flotillin 1(FLOT1)基因
Cot inhibitor
Pretreatment with platelet
Hyocholic acid 547
Functional expression and mutations of c
Treatment of Gilles de la Tourette's Syndrome with haloperidol PMID 4384341
Metabolic responses in root nodules of Phaseolus vulgaris and Vicia sativa exposed to the imazamox herbicide PMID 24861929
NBD
Bumetanide impurity 2 32643
Taxifolin ameliorates iron overload
Bystander killing effect of DS
Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC
Discovery of Fluorine
miR
AMPK
Facilitated Drug Repurposing with Artemisinin
Anti
CTX
NF
Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors PMID 23711022
Sulforaphene inhibits the progression of osteosarcoma via regulating FSTL1/NF
A role for calcium in resistin transcriptional activation in diabetic hearts PMID 30353146
透明质酸酶 2(HYAL2)基因
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway PMID 38056539
Boc
BGB
D
Synthesis of Thymoquinone
Mutation within the transmembrane domain of oxidized low
SHANK 关联的 RH 域交互器(SHARPIN)基因
Mitogen
hsa
Identification and characterization of long non
Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor
5’
Janelia Fluor® 585, SE 1811539
5
Lenercept 156679
Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer PMID 29104081
S100a4 Rat Pre
Precision
Linezolid is superior to vancomycin in experimental pneumonia caused by Superantigen
The role of dam methyltransferase in the control of DNA replication in E. coli PMID 2203541
Ibuprofenamine free base (Ibuprofen diethylaminoethyl ester)
The intraperitoneal administration of MOTS
Contributions of Protease
Nisin Z
Z
Cholecystokinin
fat
4
SCID mice
hsa
hsa
Hyaluronidase 2/HYAL2 蛋白, Human (HEK293, His)
Nisin Z 137061
Sulindac (Standard)
Lipoxygenase
bladder
Nisin Z
5,5& 039;
P Glycoprotein 抗体 (YA5626)(P Glycoprotein Antibody (YA5626))
iCo 008
5,5& 039;
CJ
NCI
cGAS
SC58451
DMT
cGAS
菲尼酮
妥布霉素 (Standard)
FITC
Urease, Jack bean
BAPTA tetramethyl ester (Tetramethyl 1,2
TA
change
eicosanoid
1
allergic asthma
2′
3,5
DMT
ALR
ALR6
Inhibitory effect of a novel quinolinone derivative, TA
PD 128907
TA 270
5’
Sequestosome
光甘草定
XO/COX/LOX
ST8SIA1 Regulates Tumor Growth and Metastasis in TNBC by Activating the FAK
FKBP
PSC 诱导系列
ADC Cytotoxin
1
CFT8634
Mesyl Salvinorin B
XAP044
BW B70C
CV1808 (2
AMN082 (Standard)
N6
Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway PMID 29663662
Effects of Resveratrol, Lovastatin and the mTOR
ICSN 3250
L
SDZ
诺斯卡品
CRIPT
CPPG
Pia Mater
PIP3
KB 5666
EA
Cyclic
renal cell carcinoma
MicroRNA
Effects of valerate on intestinal barrier function in cultured Caco
Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity PMID 30006525
Mechanism of USP11 regulated SIRT3/ROS in drug resistance of acute myeloid leukemia PMID 40736712
Exosomes derived from umbilical cord mesenchymal stem cells alleviate viral myocarditis through activating AMPK/mTOR
PF
Asthma
MP 1202
BTK
PSB
stem
Prednisolone F
paragangliomas
CAI0019
A genome
Function of low ADARB1 expression in lung adenocarcinoma PMID 31491024
Elevated FBXL6 activates both wild
YQA14
Bevenopran (CB
XAP
COX
Everolimus 159351
ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma PMID 33202906
non
VU6028418
ICSN3250 hydrochloride 1561902
Loperamide phenyl
Autophagy
Steroid hormone receptors, exome sequencing and treatment responsiveness of breast cancer patient
electrogenerated chemiluminescence
Methoxyethyl
地塞米松
CMI977 (LDP977)
Attenuation of everolimus
ICSN3250
NBD
Acyltransferase
Thiazolobenzimidazole (NSC
Lamivudine triphosphate (3TCTP)
Tanshinone IIA attenuates sepsis
mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells PMID 30054335
Everolimus
Dmt
KB
PCC0208017
Therapeutic Drug Monitoring of Everolimus Using Volumetric Absorptive Microsampling and Quantitative Dried Blood Spot Methods with LC
Epidermal and dermal cell
halitulin
Mitophagy
地塞米松
Gastric cancer cells
Ramulosin
Ferulic acid attenuates Sarcopenia progression by inhibiting peroxisomal ACOX1 PMID 40816648
Luteolin inhibits inflammation and M1 macrophage polarization in the treatment of Pseudomonas aeruginosa
Disulfide
U
ATP
lysine residues lactylation
PD 156252
Auroglaucin
酞紫
HPV
GABAA receptor agent 6
Glucocorticoid Receptor
LK 11
stroke
The protective role of adipogenic lineage precursors in maintaining bone marrow redox homeostasis in a mouse model of prenatal dexamethasone exposure PMID 40845776
mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA
Salmiac (Pharmaceutical primary standard, USP)
WAY
CD11b 抗体 (YA4648)(CD11b Antibody (YA4648))
aminosteroid
12(S)
VGSC subtype
MEFs
MCE
reverse
KF26777 free base
2
KT
antidiabetes
Targeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy PMID 41390689
SR144528
Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat PMID 7268408
astrointestinal system
glycoside
3’
Peptide E and other proenkephalin
anti
supplements
Cholesterol
VIP(6
Design, synthesis, and biological evaluation of novel matrix metalloproteinase inhibitors as potent antihemorrhagic agents from hit identification to an optimized lead PMID 25686153
ATP disodium salt, 100mM Solution, PCR Grade (Adenosine 5'
CAB7
Targeting YTHDF2 inhibits tumorigenesis of diffuse large B
In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection PMID 22354300
N
含锌指和 BTB 域 18(ZBTB18)基因
Design, synthesis and biological evaluation of novel 4
PPARγ Agonist Pioglitazone Prevents Hypoxia
Every road leads to Rome therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell
Iron oxide nanoparticles loaded with paclitaxel inhibits glioblastoma by enhancing autophagy
Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation PMID 39932187
Contribution of the CK2 Catalytic Isoforms α and α' to the Glycolytic Phenotype of Tumor Cells PMID 33477590
Salicylic acid
Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in goat male germline stem cells PMID 33420764
Single
Monoisodecyl Phthalate
ID4 predicts poor prognosis and promotes BDNF
Plasmodiumfalciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity PMID 40628257
dpy
Succinimide
Butyrolactone II 87414
TIM
The Antioxidant and HDAC
HLY78 854847
Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors PMID 33207205
MCE
GTP binding regulates cellular localization of Parkinson's disease
Estragole prevents gastric ulcers via cytoprotective, antioxidant and immunoregulatory mechanisms in animal models PMID 32750650
p
Subtype selective substrates for histone deacetylases PMID 15456267
SP4e
Soft X
Upregulation of LXRβ/ABCA1 pathway alleviates cochlear hair cell senescence of C57BL/6 J mice via reducing lipid droplet accumulation PMID 39890652
VDAC1 is a target for pharmacologically induced insulin hypersecretion in β cells PMID 40512624
Maintenance therapy with peginterferon alfa
Biotin
TEX264 Human Pre
能量代谢 (Energy Metabolism)
Cyclosporin A 59865
Bromoacetamido
Vanillylamine
TAS
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics PMID 34936468
Pendimethalin
Crosstalk Between Gastric Cancer and Adjacent Mucosa Reveals EDN1
Sacubitril/Valsartan Decreases Atrial Fibrillation Susceptibility by Inhibiting Angiotensin II
USP7 V517F mutation as a mechanism of inhibitor resistance PMID 40087304
Human congenital cataract mutation in MYH9 alters F
1
Radionuclide
ADX71441 1207440
Enhanced NK cell activation via eEF2K
Novel pyrimidinic selenourea induces DNA damage, cell cycle arrest, and apoptosis in human breast carcinoma PMID 29908443
Cinnamic Acid, Perillic Acid, and Tryptophan Metabolites Differentially Regulate Ion Transport and Serotonin Metabolism and Signaling in the Mouse Ileum In Vitro PMID 38928404
Cyclosporin A improves the hyperosmotic response in an experimental dry eye model by inhibiting the HMGB1/TLR4/NF
MurA
DNA 5
Targeting CD96 overcomes PD
Sovesudil (locally acting rho kinase inhibitor) for the treatment of normal
NEDD4 样 E3 泛素蛋白连接酶(NEDD4L)基因
S100 proteins in cancer PMID 25614008
Novel β
SGK2 Recombinant Human Active Protein Kinase
3
IMA
Fentonium bromide
Human IL11 mRNA
(±)15
Ensartinib dihydrochloride 2137030
Circular RNA PVT1 regulates cell proliferation, migration and apoptosis by stabilizing c
Novel lncRNA LncMSTRG.11341.25 Promotes Osteogenic Differentiation of Human Bone Marrow Stem Cells via the miR
Mechanistic Studies on the Role of IL
Matrix Stiffness Regulates Interleukin
αB
Imipenem
Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum PMID 22345351
SEP
Cis
Ap1s2 Rat Pre
The IL
Nerol mitigates dexamethasone
Proteasome Inhibitor MG132 Enhances Cisplatin
Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia
Slamf7
Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors PMID 37404982
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR
Induction of ASC pyroptosis requires gasdermin D or caspase
Regulation of ATP binding cassette transporter A1 (ABCA1) expression cholesterol
Bromo
Niguldipine monohydrochloride 119934
含 UbiA 异戊二烯基转移酶结构域 1(UBIAD1)基因
Gefitinib impurity 5 199327
Function and mechanism of GBP1 in the development and progression of cervical cancer PMID 38167153
Zearalenone 17924
Interaction of acriflavine with DNA and RNA PMID 5364719
STT3B promotes porcine epidemic diarrhea virus replication by regulating N
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