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Augmenting Intracellular Cargo Delivery of Extracellular Vesicles in Hypoxic Tissues through Inhibiting Hypoxia
MK
Potential antidepressive properties of amantadine, memantine and bifemelane PMID 8361950
The gain
(±)
2’
C
Venlafaxine
Protective effects of di
ELF97 phosphate (ELFP)
SAP30 结合蛋白（SAP30BP）基因
NSC 57148
LDHA
(R)
Flurofamide a potent inhibitor of bacterial urease with potential clinical utility in the treatment of infection induced urinary stones PMID 7038144
A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti
胃泌素（GAST）基因
pan
Cryoprotectant toxicity in Caenorhabditis elegans PMID 30527584
Graphene Quantum Dots Disrupt Embryonic Stem Cell Differentiation by Interfering with the Methylation Level of Sox 2 PMID 33569944
Dynamic redistribution of AMPA receptors toward memory
3’
A multi
Gardenifolins A
Terfenadine combined with epirubicin impedes the chemo
5
Protamine sulfate down
Nonlytic Quasi
Screening and validation of 3'
Trifarotene 895542
Aucubin protects mouse cochlear hair cells from cisplatin
Slc25a1 Mouse Pre
Luciferase reporter mycobacteriophage (TM4 GeNL) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex PMID 40833127
Sec
N6
Fmoc
Recombinant human brain
N
KUS121 1357164
四跨膜蛋白 4（TSPAN4）基因
Dendrotoxin K 119128
Cholesterol Homeostatic Regulator SCAP
Arginase inhibition promotes wound healing in mice PMID 21975291
叉头盒 M1（FOXM1）基因
Selective antagonism of calcium channel activators by fluspirilene PMID 1696149
11
Tyrosine
Ubiquitination regulates ER
无名指蛋白 31（RNF31）基因
Boosting Energy Deprivation via Synchronous Interventions of Oxidative Phosphorylation and Glycolysis for Cancer Therapy with 1,8
锥蛋白（TPRN）基因
Mitosis. Microtubule detyrosination guides chromosomes during mitosis PMID 25908662
Loss of YB
2
Compound Phyllanthus urinaria L Inhibits HBV
Resveratrol one molecule, many targets PMID 18421779
Chitosan Oligosaccharides Alleviate Colitis by Regulating Intestinal Microbiota and PPARγ/SIRT1
Coumberol 878019
Effects of enclomiphene and zuclomiphene on basal and gonadotrophin
H
SR146131 a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization PMID 10215649
1,2,3,4,6,7,8
Ginkgolic acid inhibits CD8+ T cell activation and induces ferroptosis by lactate dehydrogenase A to exert immunosuppressive effect PMID 40727944
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease PMID 17934471
HIPK2 sustains inflammatory cytokine production by promoting endoplasmic reticulum stress in macrophages PMID 33101464
Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance PMID 36401637
18 1 PE CF (1,2
ARL14EP Human Pre
Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model PMID 21521784
KIR2DL5/CD158f 蛋白, Human (HEK293, Fc)
Effects of piperonyl butoxide on exploratory behaviour in female mice PMID 30871449
Research on the resistance of isoviolanthin to hydrogen peroxide
SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist PMID 7714789
Toward a Bactericidal Oral Drug Combination for the Treatment of Mycobacterium abscessus Lung Disease PMID 40168319
Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas PMID 15905200
Regulation of Wnt signaling during adipogenesis PMID 12055200
Identification of circular RNAs and functional competing endogenous RNA networks in human proximal tubular epithelial cells treated with sodium
Keap1
RAC2 蛋白, Human (His)
Structure
N
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans PMID 19330009
SIRP alpha V5/CD172a 蛋白, Human (HEK293, His, Avi)
3’
(3S,5S)
Erythro
The circadian clock protein Rev
Cepharanthine inhibits migration, invasion, and EMT of bladder cancer cells by activating the Rap1 signaling pathway in vitro PMID 38883391
Signaling through hepatocyte vasopressin receptor 1 protects mouse liver from ischemia
Zoliprofen (480156
Essential role for STAT3/FOXM1/ATG7 signaling
Lymecycline 992
Antiangiogenic effects of AG36, a triterpenoid saponin from Ardisia gigantifolia stapf PMID 32643027
Serotonin regulates brain
CXCR4
The NAMPT inhibitor FK866 reverts the damage in spinal cord injury PMID 22490786
MOMIPP 1363421
Glucocorticoid
Determination of mRNA half
Molecular control of PDPNhi macrophage subset induction by ADAP as a host defense in sepsis PMID 39903516
Inhibition of dopamine beta oxidase by adrenalone PMID 13899905
Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3
Synthesis and biological evaluation of 4,6
Phenserine PMID 17594192
Adiponectin suppression of late inflammatory mediator, HMGB1
2
CD300LF+ microglia impede the neuroinflammation following traumatic brain injury by inhibiting STING pathway PMID 38965803
5,7,8
胞质铁硫组装组分 1（CIAO1）基因
Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl
Matrix metalloproteinases
MCE
MCE
Apecotrep
Ddit3
β
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin
CC
R 763
PAA
Niemann
10
(Rac)
Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis PMID 17201926
CBP/p300
PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation PMID 34759263
Diclofop
Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate
Neobulgarone E 315209
1
Gfod2
BMP10
STMN3 Human Pre
术后疼痛 (Postoperative Pain)
Encainide 66778
Muti
BMP
C.I. Disperse orange 33 69472
2,6
Exposure to both formaldehyde and high relative humidity exacerbates allergic asthma by activating the TRPV4
Bensulfuron
Oxoflaccidin 121817
Ganolucidic acid A 98665
Anti
Niravoline 130610
聚 (ADP
MCE
Radicinol 65647
LPA5 antagonist 3
Gastrazole 862583
Conformational Plasticity of Cyclic Ras
转录激活因子和发育调节因子 AUTS2（AUTS2）基因
遗迹样家族成员 1（VGLL1）基因
26239
TAU
Furfuryl acetate (Standard) (乙酸糠醇酯 (Standard))
D
Primate model
Synthesis and anti
MCE
转录因子 CP2（TFCP2）基因
Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL
丝裂原活化蛋白激酶激酶激酶激酶 1（Map4k1）基因
Pilocarpine mediated excessive calcium accumulation leads to ciliary muscle cell senescence and apoptosis PMID 39120551
Development of selective inhibitors of necrosis PMID 20848666
L
Trelagliptin impurity 2 1261686
Identification of small molecules that induce apoptosis in a Myc
3
Bifenox 42576
LY
BTM
Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment PMID 40389372
Antitumor agent
MCE
Nilestriol 39791
( )
细胞周期蛋白依赖性激酶样 3（CDKL3）基因
Androgen receptor antagonist 4
2
subgenomic
QN523
The benzoylphenylurea derivative BPU17 acts as an inhibitor of prohibitin and exhibits antifibrotic activity PMID 39182665
2'
4
Denudatine 26166
27156
(±)
Synergistic Activation of LEPR and ADRB2 Induced by Leptin Enhances ROS Generation in TNBC Cells PMID 39164083
Psoromic acid 7299
Comparative analysis of the dual EGFR
HEPPSO 68399
Glemanserin 107703
R547 741713
Tri
4
细胞色素 P450 家族 27 亚家族 A 成员 1（CYP27A1）基因
MCE
生长抑素受体 4（SSTR4）基因
SLU
radiodiagnostic
OChemsPC 155401
MCE
(R)
eIF4A3
Enah/Vasp
Ingenol
HAX1 Human Pre
Dibromochloroacetamide 855878
ADC Cytotoxin
Methyltetrazine
Cga
kynurenine pathway
PF
Marcfortine A 75731
Candicine
Garcinone
Effects of promethazine HCl on osteoporotic femora of adult castrated male rats PMID 3414364
α
PARP
A dendritic cell
异丙基邻苯二酚
6
Fungal metabolites. Part 14. Novel potent immunosuppressants, mycestericins, produced by Mycelia sterilia PMID 8195042
Pacidamycin 3 121280
5
Mdh2
Roxindole, a dopamine autoreceptor agonist, in the treatment of positive and negative schizophrenic symptoms PMID 7916543
Rhodamine B thiolactone 111883
POU 类 3 同源盒 2（POU3F2）基因
Pipercroside B
Tanuxiciclib trihydrochloride 1983984
1,4
GelMA Hydrogel Encapsulating iPSC
Gingerdione 61871
Cap
半胱氨酰白三烯受体 2（Cysltr2）基因
Dexbrompheniramine
Viniferol D 625096
Fgf13
AD 4743 87858
Bombyx mandarina
溶质载体家族 38 成员 7（SLC38A7）基因
1,2
80823
AB
hydrolyzing
Baohuoside I suppresses invasion of cervical and breast cancer cells through the downregulation of CXCR4 chemokine receptor expression PMID 25407882
Leucyl
A 23887 61955
DMT
MSP
Diethyl 7
Displurigen 96156
A study on the regulation of growth hormone release from the pituitaries of rats in vitro PMID 6109625
tert
Pralatrexate impurity 1 146464
Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF
YB1 抗体（YB1 Antibody）
Nuclear Factor
The Role of NO Synthase, MPT pore, and Protein Kinase A in the Cardioprotective Effect of the Opioid Receptor Agonist Deltorphin II PMID 37160797
Delavinone 96997
Tropolone alkaloids from Colchicum kurdicum (Bornm.) Stef. (Colchicaceae) as the potent novel antileishmanial compounds; purification, structure elucidation, antileishmanial activities and molecular docking studies PMID 32353376
Prostaglandin E2 isopropyl ester 71845
MCE
HDAC
Elacridar improves sunitinib efficacy in colorectal cancer models PMID 40639493
二孔段通道 1（TPCN1）基因
7
The suppressive role of phytochemical
20 4 PG sodium 474943
Perakine 4382
JS
MCE
Hongoquercin A 213338
(R)
O
3'
CID 1375606 313493
Identification of inflammation
PAP 248
Flutriafol 76674
BTK ligand 11
MCE
三叶因子 1（TFF1）基因
OAT177
D 131 652145
MCE
Bifidobacterium animalis subsp. Lactis BX
toll 样受体 7（TLR7）基因
小分子化合物抗体 (Small
Modular synthesis of new C
Determination of simazine, terbuthylazine, and their dealkylated chlorotriazine metabolites in soil using sonication microextraction and gas chromatography PMID 11048866
BRD4 Inhibitor
Lactocin 705β 929219
活化 C 激酶 1 受体（RACK1）基因
Neurogranin 28
MMBC 137350
7
SRI
Fpr1
Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation
Lactosyl
4
MCE
MCE
Ethylene glycol
Patrinoside aglucone 76319
PARP1 抗体 (YA245)（PARP1 Antibody (YA245)）
Dox
Antipain dihydrochloride 37682
Adam28
H
Z
MCE
Oligopeptide
1,7
AHL
Nile blue chloride 2381
E3 Ligase Ligand
Effects of the Phosphodiesterase
Tetradecyl
10
2
KWWCRW 292148
Tnfrsf21
Ethyl 8(Z)
核糖核蛋白 4B（LARP4B）基因
1
Methyl 2
Huwentoxin XVI 1600543
Raptor
Chimeramycins new macrolide antibiotics produced by hybrid biosynthesis PMID 6860432
Adam19
Preptin (rat) 315197
(
c
Molecular Signatures of CB
Z
DCLK1
Boc
BiPNQ 313513
Carburazepam 59009
Cyp27a1 Rat Pre
MCE
Bumetanide impurity 1 28328
S 135 104679
KRO
7
DPP
M344 251456
MCE
Rauvoyunine C 1211543
Flotufolastat
CGS 35601 849066
2,3
Methionine Adenosyltransferase (MAT)
缺口受体 1（Notch1）基因
Dihydroperaksine 16100
SR 4330 20028
K
Prostaglandin K2 275816
Evidence for the occurrence and formation of diazonium ions in the Agaricus bisporus mushroom and its extracts PMID 7201479
Cyp27a1 Mouse Pre
21
Voafinidine 180059
FKBP 脯氨酰异构酶 4（FKBP4）基因
CCG
TTN 蛋白, Human (His)
ASCT2
MCE
H2A.X 变体组蛋白（H2AX）基因
Factor B
Taxumairol B 142203
Ace
Ganglioside sialidase (AuSialidase M2) (Sialidase isoenzyme M2，神经节苷脂唾液酸酶（AuSialidase M2）)
Phosphatidylinositol phosphodiesterase (磷脂酶C，磷脂酰肌醇特异性)
MDA
CGP 54626 hydrochloride 149184
Irf6
Trim21
POU3F2 Human Pre
MCE
Phenochalasin A 253129
MCE
Glucosamine–biotin adduct 1825360
TC OT 39 479232
Ibopamine hydrochloride (SB 7505 hydrochloride)
脱氧核糖磷酸醛缩酶（DERA）基因
GBR
RU
KRAS G12D ligand
H
LDL 受体相关蛋白 10（LRP10）基因
Lactate dehydrogenase a
L
载脂蛋白 L2（APOL2）基因
前蛋白转化酶枯草杆菌蛋白酶/kexin 7 型（PCSK7）基因
N
GLUT
Influenza HA (518
PF
4
IL
BAY 3827
磷脂酶 D2（PLD2）基因
4,4'
Ethyl 6
Tfcp2 Rat Pre
蛋白磷酸酶 1 调节抑制因子亚基 1B（PPP1R1B）基因
多西紫杉醇
上游结合蛋白 1（UBP1）基因
16,17
Phenylethanolamine A
(Z
唾液酸结合 Ig 样凝集素 12（SIGLEC12）基因
Dbi Rat Pre
MCE
IKAROS 家族锌指 1（IKZF1）基因
EGIS
YS370
Roxindole
Monoamine oxidase from genes to behavior PMID 10202537
Discovery of a first
CS
芍药苷
Piperkadsin A 895543
Carboxypeptidase B (MS grade) (EC 3.4.2.2 (MS grade)，羧肽酶 B（MS 级）)
Antifungal agent 129
TD
MCE
CYP1B1
H1975
Chlorpheniramine
Dementia with Lewy bodies
NSC 90469 (Standard) (3,5
Tocolytic activity of formoterol against premature delivery in mice PMID 12542893
ERGIC 和高尔基体 3（ERGIC3）基因
BTX306 2230747
MCE
uPAR antibody (huATN
High potency inhibition of hERG potassium channels by the sodium
Adam12 Mouse Pre
16 0
9240
OPT80
L
Alpinin A 2151847
Tofacitinib impurity 32 477600
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice PMID 38129407
Ifna4 Mouse Pre
Ac
Gfod2 Rat Pre
张力蛋白 2（TNS2）基因
Cholesteryl brassidate 79728
A third
ON
IL
Cytidine Diphosphate
Antifungal agent 32 1809167
Virus
蛋白激酶 C, theta（Prkcq）基因
Mas7
(S)
Diethylstilbestrol activates CatSper and disturbs progesterone actions in human spermatozoa PMID 28031325
Delivery of class I and class II MHC
CS
Screening and discovery of nitro
Comparative studies on the in vivo action of 6
Dithiocarbamates combined with copper for revitalizing meropenem efficacy against NDM
Expression of interleukin
2,8
Inhibitory effects of cornuside on human liver cytochrome P450 enzymes PMID 39939490
Cloquintocet
Butyl 2
突触体相关蛋白 29（SNAP29）基因
DEZ
TPCN1 Human Pre
Quercetin Alleviates Chronic Urticaria by Negatively Regulating IgE
Down
Amyloid β
ATPase H+ 转运 V1 亚基 D（ATP6V1D）基因
Calm2
核运输因子 2（NUTF2）基因
Hspa2 Mouse Pre
CKAP4 is a potential therapeutic target to overcome resistance to EGFR
The toxicity of spermine and spermidine to cells in culture PMID 4895015
Asparagine Synthetase 抗体 (YA608)（Asparagine Synthetase Antibody (YA608)）
Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease PMID 34775946
1
Polyethylenimine
Maurocalcine interacts with the cardiac ryanodine receptor without inducing channel modification PMID 17537000
CAY10464 (AHR antagonist 7)
RS09
MCE
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