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Ticagrelor impurity 5 1863036
N
Emodin attenuates silica
Diphenhydramine N
VEGFR1
Evaluation of the disinfection effect and mechanism of SO4•
The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma PMID 36715683
Discovery of ZN
Toll
O
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines PMID 17636412
The potential immunotoxicity of emamectin benzoate on the human THP
5
(S)
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases PMID 16866524
Valdecoxib 181695
The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity PMID 29315511
Pias1 Mouse Pre
Identification of Potent, Selective, Cell
CDK1
Distribution analysis of epertinib in brain metastasis of HER2
Synergistic enhancement of anticancer effects by periodontal ligament stem cell exosomes and oxaliplatin via apoptosis induction and protein modulation PMID 40834748
Association of Active Renin Content With Mortality in Critically Ill Patients A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Trial PMID 37947484
Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing PMID 38770531
Extracellular RNA promotes leukocyte recruitment in the vascular system by mobilising proinflammatory cytokines PMID 22836360
Phase 1, Single
Lifitegrast
Charge
ALKBH8
BACE2
Histone acetyltransferase P300 deficiency promotes ferroptosis of vascular smooth muscle cells by activating the HIF
Coryximine 127460
BMS
Hepatic Lactate Dehydrogenase A An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria PMID 33912759
The Gab2
16 0
4'
Novel potential agents for human cytomegalovirus infection synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides PMID 10197958
Sodium tartrate dibasic dihydrate (Standard)
4
Functionalized curcumin analogs as potent modulators of the Wnt/β
含锌指和 BTB 结构域 7B（ZBTB7B）基因
WD 重复域 62（WDR62）基因
Dextran sulfate sodium salt (MW 5000) 9011
Benzyl
Chloroquinoxaline sulfonamide (Chloroquinoxaline)
ISG15 depletion enhances oHSV
Chloroquine and Rapamycin Augment Interleukin
Fucoxanthin ameliorates Propionibacterium acnes
Macelignan Improves Functional Recovery After Spinal Cord Injury by Augmenting Autophagy via the AKT
AZD1080 612487
Connexin43 reduces LPS
Seribantumab, an Anti
含卷曲螺旋结构域 9（CCDC9）基因
Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing PMID 30498132
Diversity in arrestin function PMID 19597700
Circular RNA ITCH increases sorafenib
Synthesis and antiprotozoal activity of dicationic 2,6
DNA 结合抑制因子 3（ID3）基因
A SARS
RSV
DNMT1, a Novel Regulator Mediating mTORC1/mTORC2 Pathway
multiplication
Exercise Ameliorates Atherosclerosis via Up
Establishment of patient
Mechanism of neuroprotective effect of stevioside on cerebral ischemia
ATF4
Trifluridine/tipiracil hydrochloride mixture 733030
TRPC6 channel
Asporin regulated by miR
Drug Repurposing to Identify a Synergistic High
Reassessing endothelial
Characterization of three non
Maternal exposure to CeO2NPs derails placental development through trophoblast dysfunction mediated by excessive autophagy activation PMID 35292031
Helicobacter pylori CagA elevates FTO to induce gastric cancer progression via a hit
Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication PMID 40462306
Dexamethasone
PPARγ mediated lysosomal membrane permeabilization and lipophagy blockage were involved in microplastics and di (2
USP12 regulates ER stress
Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid
Bile Acid G Protein
Central memory CD4+ T cells play a protective role against immune checkpoint inhibitor
Discovery of IACS
生长停滞特异性 2 样 3（GAS2L3）基因
Polygonatum cyrtonema Hua Polysaccharide Promotes GLP
Capsaicin
Quantitative proteomics identifies FOLR1 to drive sorafenib resistance via activating autophagy in hepatocellular carcinoma cells PMID 33677528
New insights into brain injury in chickens induced by bisphenol A and selenium deficiency
Curcumol enhances the anti
檵木提取物 (Loropetalum chinense (R. Br.) Oliver)
The CRM1
(S)
沉默信息调节因子 2 相关酶类 2（SIRT2）基因
Pharmacokinetics and safety of bromotetrandrine (BrTet, W198) after single
Quassinoids isolated from Brucea javanica inhibit pepper mottle virus in pepper PMID 27686478
HIV Integrase
Aphadilactones A
Small Extracellular Vesicles from Periodontal Ligament Stem Cells Primed by Lipopolysaccharide Regulate Macrophage M1 Polarization via miR
Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models PMID 30323233
Identification of volatile active components in Acori Tatarinowii Rhizome essential oil from different regions in China by C6 glioma cells PMID 32807141
First clinical description of letermovir resistance mutation in cytomegalovirus UL51 gene and potential impact on the terminase complex structure PMID 35690130
Differentiating the Pharmacodynamics and Toxicology of Macrolide and Ketolide Antibiotics PMID 31644280
ZDHHC20 Activates AKT Signaling Pathway to Promote Cell Proliferation in Hepatocellular Carcinoma PMID 39309302
trans
Free Fatty Acids Induce Apoptosis of Mammary Epithelial Cells of Ketotic Dairy Cows via the Mito
Angelica dahurica Extracts Improve Glucose Tolerance through the Activation of GPR119 PMID 27391814
24(RS)
SQSTM1/p62 is involved in docosahexaenoic acid
mTORC1
Benzo[a]pyrene inhibits testosterone biosynthesis via NDUFA10
resveratrol
4
m
ABCC1 蛋白, Bovine (HEK293, GFP, StrepⅡ, His)
ARN25062
AChE
Neutrophil
PD
Chemical tools for epichaperome
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis
Etoposide
Bioanalytical method for evaluating the pharmacokinetics of the GCP
H
STAT3 activation of SCAP
Chemical synthesis and bioassay of anordrin and dinordrin I and II PMID 109951
Targeted Degradation of Histone Deacetylases via Bypassing E3 Ligase Targeting Chimeras (BYETACs) PMID 40529059
EOP (t18 0/28 0/18 2)
Pyraclostrobin 175013
RANBP1 promotes colorectal cancer progression by regulating pre
Stromal PLAU mediates tumor progression and informs a novel therapeutic target in triple
Demethoxydeacetoxypseudolaric acid B 82508
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets PMID 36442237
Phthalic acid bis(3,7
NLRP3
The modulatory action of loreclezole at the gamma
Investigating the effects of TRPV4 and Cav1.2 channels in 3D culture for promoting the differentiation of BMSCs at various stages PMID 40073957
Dual molecularly imprinted nanocomposite with transferrin mediated glioma targeting and cholesterol exhaustion for synergistic cuproptosis/immune checkpoint blockade/immunogenic cell death PMID 40893371
Indirubin, a bis
Central administration of Dapagliflozin alleviates a hypothalamic neuroinflammatory signature and changing tubular lipid metabolism in type 2 diabetic nephropathy by upregulating MCPIP1 PMID 37931516
Mca
Comparative analysis of pharmacological properties of xanomeline and N
Salacia macrosperma Wight提取物 (Salacia macrosperma Wight)
Cross
Butyl benzoate (n
mTOR
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice PMID 36747238
MCE
Inhibition of Toll
Irisin mitigates rheumatoid arthritis by suppressing mitochondrial fission via inhibiting YAP
Coagulation factors directly cleave SARS
Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors PMID 39811131
HS
Structural characteristics of oil
5
Preparation of the sphingolipid fraction from mycelia of Cordyceps sinensis and its immunosuppressive activity PMID 35189280
Vesicular Stomatitis Virus Glycoprotein
Aldose 1
Anti
MAGL
RAR 相关孤儿受体 β（Rorb）基因
The role of growth factors and cytokines during implantation endocrine and paracrine interactions PMID 19197806
Enzyme
Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis Insights From Genetic and Pharmacological Approaches PMID 38848078
CLN6 跨膜内质网蛋白（CLN6）基因
An IFNγ
ODN MT01
(R)
Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3
ROCK
CCNK gene deficiency influences neural progenitor cells via Wnt5a signaling in CCNK
(+)
Artesunate
Acylated Flavonoid Glycosides are the Main Pigments that Determine the Flower Colour of the Brazilian Native Tree Tibouchina pulchra (Cham.) Cogn PMID 30781526
Antitumor agent
Activation of the serotonin 5
CX
(S)
Synthesis of polyamine derivatives having non
Tyrphostin AG 1288 (AG 1288)
Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib PMID 30742664
Morin applied in speciation of aluminium in natural waters and biological samples by reversed
LSM7 同系物、U6 小核 RNA 和 mRNA 降解相关（LSM7）基因
Identification of small
Mal
琥珀酸脱氢酶复合物黄素蛋白亚基 A（SDHA）基因
Midbrain ghrelin receptor signalling regulates binge drinking in a sex specific manner PMID 40089486
Exogenous IL
Diterpenoids from the twigs and leaves of Fokienia hodginsii PMID 23691952
FM26 2407981
USP24
5,7
PXYC2
Simvastatin ameliorates adverse pregnancy by inhibiting glycolysis
Exosomes from uterine fluid promote capacitation of human sperm PMID 38680889
Sestrin2 remedies podocyte injury via orchestrating TSP
Single
Siplizumab, an Anti
Dying tumor cell
IGF1 Receptor 抗体 (YA4906)（IGF1 Receptor Antibody (YA4906)）
RNF31 Human Pre
Discovery of 4 H
Gasdermin D independent canonical inflammasome responses cooperate with caspase
SU 5402 215543
Dominant follicle
Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection PMID 39746094
T
Pimeloyl
Sonic hedgehog signaling is active in human adrenal cortex development and deregulated in adrenocortical tumors PMID 24712566
Antiproliferative activity of O4
Mass Spectrometric Characterization of HIV
Taurolithocholic acid
Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis PMID 30738829
上游转录因子 2，c
Carnosic acid enhances cisplatin sensitivity and suppresses gastric cancer progression via the TP53/SLC7A11/ALOX12 axis PMID 40696490
Co
Cross
Lipase, Aspergillus niger
3
Synthesis of Galactosyl
ADAMDEC1 promotes cervical squamous cell carcinoma by enhancing the JAK/STAT signaling pathway through modulation of TYMP PMID 39625490
MCE
A placebo
Cellular uptake of arginine
Berberine Protects against NEFA
In Situ One
ABHD6 blockade exerts antiepileptic activity in PTZ
S
BMS
arthritis
马兜铃酸 C (Standard)
Structure
FAP 抗体 (YA1442)（FAP Antibody (YA1442)）
Cyproterone acetate in the therapy of prostate carcinoma PMID 16372511
Multiparameter Optimization of Broad
ztz240 325457
Small molecule
Neuregulin
Amantadine alleviates postoperative cognitive dysfunction possibly by increasing glial cell line
Mechanism of interaction of vinca alkaloids with tubulin catharanthine and vindoline PMID 1988072
Trace amine
Lisinopril 76547
Cholesterol
Biological profile of new apoptotic agents based on 2,4
Disordered region of cereblon is required for efficient degradation by proteolysis
Cyanein
ICMT
Redox
Silencing of TXNIP attenuates oxidative stress injury in HEI
Fibroblast Activation Protein (FAP)+ cancer
The Circadian Hormone Melatonin Inhibits Morphine
Fatty acid synthase
RBPMS2 can inhibit the NLRP3 / caspase
CD73 inhibition by purine cytotoxic nucleoside analogue
neuroblastoma
Hepatic triacylglycerol lipase activities after induction of diabetes and administration of insulin or glucagon PMID 7047662
Fluorescent Dye
pocket
Contractile response
Nortriptyline (Standard)
antifungal
Diet
colorectal
hCAIX/VII
Cholecystokinin Receptor
Effect and underlying mechanism of a photochemotherapy dual
Knockdown of Mg2+/Mn2+ dependent protein phosphatase 1A promotes apoptosis in BV2 cells infected with Brucella suis strain 2 vaccine PMID 32742335
CD 5024
Flonicamid 158062
4& 039;,7
Fangchinoline
7
Manganese
Tryptophan Promotes Intestinal Immune Defense through Calcium
Vanillylamine
XPC 5462
Polyphenol
MED1 Ablation Promotes Oral Mucosal Wound Healing via JNK Signaling Pathway PMID 36362197
PZ703b
Sodium Channel
HtrA1 upregulates the expression of ADAMTS
Anti
Glucose metabolism involved in PD
DUX4 expression activates JNK and p38 MAP kinases in myoblasts PMID 36196640
The novel poly(ADP
DSG3 promotes bladder cancer growth and metastasis via AKT/GSK3β/β
METTL3 regulates LPS
Pirfenidone 53179
Betaine
Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G
Myeloid
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3
Boc
北美翠柏提取物 (Calocedrus decurrens (Torr.) Florin)
1,1' 2',1''
1
CSL
Cyclofenil 2624
1
Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway PMID 32377702
Cytotoxic Trichothecene Macrolides Produced by the Endophytic Myrothecium roridum PMID 31117520
Glycosylation
Phospho
Limonin, a novel AMPK activator, protects against LPS
Identification and characterization of 4
Calmodulin
Pyroptosis inhibitors MCC950 and VX
Genome
Enalapril
(S)
受体酪氨酸激酶
β
Mutations in fibroblast growth factor (FGF8) and FGF10 identified in patients with conotruncal defects PMID 32664970
ADC Payload
ABL1
Hydroxy
Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines PMID 20805012
S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab PMID 23804704
Muscarinic
Taste Receptor
Biotin
Synthesis, characterization, and anti
M
Pentetic acid (Diethylenetriaminepentaacetic acid，喷替酸)
Propanoic
REV
Cognition
TH588 1609960
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis PMID 33667689
Avicularin inhibits ferroptosis and improves cognitive impairments in Alzheimer's disease by modulating the NOX4/Nrf2 axis PMID 39515096
[Sar1,Ala8] Angiotensin II acetate
Cholesterol
alkamide
Dimethylarginine
XO/COX/LOX
Postmortem tissue concentrations of venlafaxine PMID 11516890
MYC 原癌基因，bHLH 转录因子（MYC）基因
Amyloid precursor protein (APP) affects global protein synthesis in dividing human cells PMID 25283437
Glypican
液相色谱
Tibolone 5630
A phosphoproteomics study reveals a defined genetic program for neural lineage commitment of neural stem cells induced by olfactory ensheathing cell
Lonafarnib synergizes with azoles against Aspergillus spp. and Exophiala spp PMID 29420769
Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism PMID 31335899
BTZO
Cyclooxygenase
Salidroside protects SH‑SY5Y from pathogenic α‑synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling PMID 31180515
Anti
Protease inhibitor Camostat Mesyalte blocks wild type SARS
[Late results of the Colonna arthroplasty] PMID 3217106
Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K
The CCL5/CCR5/SHP2 axis sustains Stat1 phosphorylation and activates NF
Hepatic PPARα function is controlled by polyubiquitination and proteasome
miR
Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor
C3a/C3aR synergies with TGF
House Dust Mite Extract, from D.farinae (屋尘螨提取物, 来源粉尘螨)
5
angina
Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis PMID 10681327
Protein Stability Effects in Aggregate
ENT
A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice PMID 36694341
Sertindole in the management of schizophrenia PMID 23861640
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non
Flecainide 54143
Baloxavir Treatment Delays Influenza B Virus Transmission in Ferrets and Results in Limited Generation of Drug
Synergistic effects of E2MATE and norethindrone acetate on steroid sulfatase inhibition a randomized phase I proof
3
Inhalable mRNA Nanoparticle with Enhanced Nebulization Stability and Pulmonary Microenvironment Infiltration PMID 39174871
Diethyl 8
Withdrawal from repeated administration of a low dose of reserpine induced opposing adaptive changes in the noradrenaline and serotonin system function a behavioral and neurochemical ex vivo and in vivo studies in the rat PMID 25445479
m
PKG
Immunostimulatory effect of spinach aqueous extract on mouse macrophage
Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy PMID 34943023
Heterophyllin B alleviates cognitive disorders in APP/PS1 model mice via the spleen
NH2
Pyrroloaryls and pyrroloheteroaryls Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase PMID 26116177
epileptiform
5& 039;
Systemic Monocyte Chemotactic Protein
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer PMID 36897957
Eltrombopag
HSD17B13
N
Buxifoliadine A 263007
Aquatic high iron induces hepatic ferroptosis in zebrafish (Danio rerio) via interleukin
Targeting TGF
N
Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan
5& 039;
SIPA1 enhances SMAD2/3 expression to maintain stem cell features in breast cancer cells PMID 33296812
cross
Ubiquitination of angiotensin
C 225
17 beta
BI3231
CAY
Pirozadil
AhyI
7
Torin1
Role of mTOR signaling in the regulation of high glucose
替鲁地平盐酸盐
smoke
GW 9578
Phenidone
Machine learning
anti
RAW264.7 cells
A
BTR2000
Antidiabetic agent 2 3052242
Monoclonal Antibody Therapy in Alzheimer's Disease PMID 38258071
Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging
The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae PMID 32579556
Loss of Presynaptic Terminal Integrity in the Substantia Nigra in Early Parkinson's Disease PMID 32767618
RILP Human Pre
肽基脯氨酰异构酶 D（PPID）基因
Exogenous IL
SOX2 knockdown slows cholangiocarcinoma progression through inhibition of transcriptional activation of lncRNA PVT1 PMID 32812642
Natural Sources and Bioactivities of 2,4
Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis PMID 26786851
硬脂酰辅酶 A 去饱和酶（SCD）基因
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry Optimization of DNA
Cryptotanshinone protects against pulmonary fibrosis through inhibiting Smad and STAT3 signaling pathways PMID 31181334
(R)
Anti
PROTAC ER Degrader
Hyperglycemia
miR
Melatonin alleviates lead
Quinoline
Design, synthesis and biological evaluation of N
Transdifferentiating Astrocytes Into Neurons Using ASCL1 Functionalized With a Novel Intracellular Protein Delivery Technology PMID 30525033
Aloperine exerts anti
gp130/IL6ST 蛋白, Rhesus Macaque (HEK293, Fc)
Centpropazine 91315
mRNA
Unveiling Natural Power Morin and Myricetin as Potent Inhibitors of Histidinol
FK
LAMTOR1 decreased exosomal PD
cephalosporin
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes PMID 22920224
DBCO
Pivalylbenzhydrazine 306
Aspirin eugenol ester ameliorates paraquat
Dacarbazine
IL
Canagliflozin alleviates LPS
Cinchonain Ia 85081
4
Purification, partial characterization and substrate specificity of a squalene cyclase from Bacillus acidocaldarius PMID 3768141
MCE
mRNA
Polyphyllin I induces rapid ferroptosis in acute myeloid leukemia through simultaneous targeting PI3K/SREBP
Nonalcoholic fatty liver disease
anorectic
The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress PMID 35503721
PAT
6
ATTECs
Starch (from corn)
干扰素 α 和 β 受体亚基 1（IFNAR1）基因
(Rac)
Tripentadecanoin
The galactose
HER2
The Novel Pan
Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice PMID 16303950
Imbricatin 84504
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis PMID 38582895
Protein expression in yeast; comparison of two expression strategies regarding protein maturation PMID 11164265
Regulation of mammalian cellular metabolism by endogenous cyanide production PMID 40033006
FGL1 蛋白, Human (HEK293, His)
Melatonin promotes differentiation and apoptosis of AML1
LKB1/AMPK axis crosstalks with Wnt/β
OSU
Autophagy induction and antiproliferative effect of a novel curcumin derivative MOMI
Physalin A induces apoptotic cell death and protective autophagy in HT1080 human fibrosarcoma cells PMID 23647462
N
The androgen receptor couples promoter recruitment of RNA processing factors to regulation of alternative polyadenylation at the 3' end of transcripts PMID 36043441
Przewalskin 119400
PreQ1
Resveratrol, an Nrf2 activator, ameliorates aging
EloA promotes HEL polyploidization upon PMA stimulation through enhanced ERK1/2 activity PMID 34697988
2,3,6
Inhibitory effect of baricitinib on microglia and STAT3 in a region with a weak blood
RO
Darigabat 1614245
5
4
RAS 蛋白激活蛋白样 1
The Src1
GSK189254A 720690
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