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The CoREST complex is a therapeutic vulnerability in malignant peripheral nerve sheath tumors PMID 39229179
Heparin affects human bone marrow stromal cell fate Promoting osteogenic and reducing adipogenic differentiation and conversion PMID 25959412
m
JC
cAMP 反应元件结合蛋白 3 like 1（CREB3L1）基因
LXR modulator
Isoproturon
Isoxicam 34552
WLBU2 acetate
The identification of c
Ginsenoside C
siRNA silencing of PD
SAR studies of 2
Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB
Remdesivir de(ethylbutyl 2
Impairment of retrograde neuronal transport in oxaliplatin
Betaine
BCMA/TNFRSF17 Trimer 蛋白, Human (HEK293, His
Design, synthesis and biological evaluation of 7
Adiponectin receptor agonist AdipoRon modulates human and mouse platelet function PMID 35918410
KEL/Kelch
Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa in vivo antimalarial activity and X
Immune response in mice that lack the interferon
Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP
Antibody
Synthesis and molecular docking studies of novel 2
Iron(II) succinate 10030
Cyclic RGD modified dextran
Mesenchymal stem cell
RS 39604
Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP
ARC19499 1350667
Risedronic acid
Loxapine inhalation powder a review of its use in the acute treatment of agitation in patients with bipolar disorder or schizophrenia PMID 23740380
Antinociceptive effects of methyl jasmonate in experimental animals PMID 21387099
Overexpression of RBM4 promotes acute myeloid leukemia cell differentiation by regulating alternative splicing of TFEB PMID 39214303
Anti
mTOR signalling controls the formation of smooth muscle cell
Chiral 6
乌利沙星
Ac
纳米抗体 (Nanobodies)
Retinoprotective Effect of Wild Olive (Acebuche) Oil
Aminooxyacetic acid hemihydrochloride 2921
CUL3 Human Pre
N6
Firastotug 2750031
Palmitelaidic acid 10030
Mesenchymal Stem Cell
Enpp7
Blocking peptidyl arginine deiminase 4 confers neuroprotective effect in the post
Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑κB signaling pathways PMID 32626938
Paliperidone protects prefrontal cortical neurons from damages caused by MK
BQCA 338747
Lopinavir 192725
IDO
Filgotinib maleate 1802998
ITGA4 Contributes to 5
meso
Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma PMID 18477505
The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo PMID 28659588
Synthesis and bioactivity of 4
Targeted neural stem cell
Epigallocatechin
3
CXCR2 antagonist 8 182498
Methyl 13(S)
Oral Nanoparticles Exhibit Specific High
Bruceine D inhibits hepatocellular carcinoma growth by targeting β
miR
Identification and characterization of plant
Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA
Artesunate
CD276
Synthesis and antitubercular evaluation of reduced lipophilic imidazo[1,2
Sulforhodamine 101 induces long
GNE
羧肽酶 N 亚基 1（CPN1）基因
18 0 Aminoethyl PC
Noscapine and its Analogs as Chemotherapeutic Agent Current updates PMID 27237331
Ro 31
CM
Barnidipine hydrochloride 104757
fluorescence emission
DMTr
Cevimeline hydrochloride 107220
Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung PMID 26937637
KCNN4 Human Pre
lack of calcium
Okicenone
RET
Amlodipine aspartic acid impurity (Standard)
Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma PMID 30315229
Ro 31
Dual FLT3 inhibitors Against the drug resistance of acute myeloid leukemia in recent decade PMID 31207462
Ginsenoside metabolites, rather than naturally occurring ginsenosides, lead to inhibition of human cytochrome P450 enzymes PMID 16547074
Tanshinone IIA promotes ferroptosis in cutaneous melanoma via STAT1
Kifc3 Rat Pre
Butoconazole 64872
CREB3L1
多萜醇激酶（DOLK）基因
LXR beta
Magnetic solid
Palbociclib monohydrochloride 827022
poly
Dysfunction of programmed embryo senescence is linked to genetic developmental defects PMID 37017267
Cyclolinopeptides, cyclic peptides from flaxseed with osteoclast differentiation inhibitory activity PMID 26923696
ML377
target identification
PRT
Dxd 1599440
BMMSCs
18
CREB3L1 Human Pre
15
18 0 Aminoethyl PC 2389048
18 0 Aminoethyl PC
Selective inhibition reveals cyclin
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus PMID 35948546
(S)
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis PMID 22726834
洛匹那韦
Chelator
奥英妥珠单抗
Poly(ethylene glycol) 2
4
H3K9me2
ADP
动脉粥样硬化 (Atherosclerosis)
甲磺酸去铁胺 (Standard)
Biology and Role of Extracellular Vesicles (EVs) in the Pathogenesis of Thrombosis PMID 31212641
Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV
HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT PMID 31160757
Thalidomide
AMX208
Terazosin
estrogen receptor
Potassium thiocyanate
Boc
TPRN Human Pre
Biotin
Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs PMID 16334957
NHC
MCE
PD 125967 128139
Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions PMID 40858584
Amphiregulin Mediates Epithelial Cell
Technical Support
Salvigenin mitigates neuronal ferroptosis by binding to PI3K and enhancing the interaction between VCP and PI3K in the repair of spinal cord injury PMID 40865346
Time
DOR agonist 2
Potassium acetate, meets USP testing specifications
fluorometer
Abemaciclib is effective in palbociclib
Browniine 5140
Isosteviol (Standard) ((
Up
Inhibition of TNF
In Vivo Efficacy of a Cocktail of Human Monoclonal Antibodies (CL184) Against Diverse North American Bat Rabies Virus Variants PMID 30270905
poly
Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells PMID 2386550
YTHDF1 loss in dendritic cells potentiates radiation
Discovery of 1
Mitochondrial STAT3 exacerbates LPS
Discovery of bufadienolides as a novel class of ClC
A complete map of human cytosolic degrons and their relevance for disease PMID 40463067
Guidelines for the treatment of acidaemia with THAM PMID 9506241
(E)
Synovial mesenchymal stem cell
HAUS augmin 样复杂亚基 8（HAUS8）基因
CD28
Ivabradine induces RAD51 degradation, potentiating PARP inhibitor efficacy in non
Mordant brown 1 3564
Satumomab (沙妥莫单抗)
Effects of central neuropeptide S in the mouse formalin test PMID 20603169
Galactose Oxidase, Dactylium dendroides 9028
Human CCR1 mRNA
Design and Characterization of Bioactive Bilayer Films Release Kinetics of Isopropyl Palmitate PMID 32722329
HCV
Glucagon
Paquinimod 248282
Down
BCL2 相关转录因子 1（BCLAF1）基因
Cephaibol A 304911
Fenthion sulfone 3761
Identification, Structure
Tropinone
Amino
TRPM3_miR
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer PMID 27563814
Autophagy and PPARs/NF
MAB21L2 蛋白, Human (His)
Structure
VCP 抗体 (YA4098)（VCP Antibody (YA4098)）
Effects of oral and vaginal administration of levonorgestrel emergency contraception on markers of endometrial receptivity PMID 20139427
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome
Arachidyl myristate
CRNDE enhances the expression of MCM5 and proliferation in acute myeloid leukemia KG
(S)
Annulatin 1486
Boscalid 188425
Potent, structurally constrained agonists and competitive antagonists of corticotropin
Imatinib a breakthrough of targeted therapy in cancer PMID 24963404
Optimization of novel combi
MICAL
(R)
On codon
Thalidomide
Luteolin targets peroxiredoxin 2 to augment T
alpha
The fidelity of spin trapping with DMPO in biological systems PMID 21246623
白介素 1 受体相关激酶 2（IRAK2）基因
NVP
Sacubitrilat 149709
含约瑟芬域 2（JOSD2）基因
Amelioration of metabolic disorders in H9C2 cardiomyocytes induced by PM2.5 treated with vitamin C PMID 36815321
Synthesis, biological evaluation, and structure
6
TUFT1 regulates cancer progression by suppressing centrosome amplification and mitotic spindle multipolarity PMID 41022752
Modulation of synaptic function by cGMP and cGMP
Pirarubicin 72496
SW203668 TFA 2117405
Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin
Ndrg1 Mouse Pre
Design, synthesis and biological evaluation of substituted aminopyridazin
DNA/RNA Synthesis
Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa PMID 29997585
IFNA4 Human Pre
RS
TXA2 Inhibitor
Enhancing T cell anti
Dopamine receptor pharmacology PMID 7940991
PI3Kγ inhibitor 1
Selective up
Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation PMID 36443288
Salmeterol xinafoate 94749
MCE
Notch4 signaling limits regulatory T
Benzoquinazoline derivatives as new agents affecting DNA processing PMID 21216603
Kistamicin A
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB
Cucurbitacin D impedes gastric cancer cell survival via activation of the iNOS/NO and inhibition of the Akt signalling pathway PMID 29658590
Doravirine 1338225
跨膜蛋白 222（TMEM222）基因
DOTA
CDK4/6 inhibitor
SCID mice
Sirtuin
CC
A designer hyper interleukin 11 (H11) is a biologically active cytokine PMID 22433466
BD140A
苏丹红Ⅲ
Macelignan (Standard)
MicroRNA
[<sup>3</sup>H]CHIBA
安五脂素 (Standard)
Hydrolyzed Glutenin (水解谷蛋白)
MCE
CC0651 1319207
Propargyl
Salbutamon
损伤特异性 DNA 结合蛋白 2（DDB2）基因
DGY
Synthesis and antibacterial activity of isothiazolyl oxazolidinones and analogous 3(2H)
Ifng
Birc6 Rat Pre
Rapamycin regulates cholesterol biosynthesis and cytoplasmic ribosomal proteins in hippocampus and temporal lobe of APP/PS1 mouse PMID 30798110
BAK plays a key role in A
Synthesis and biological evaluation of 2',4'
AVX 13616
IFNL3
In vitro and in vivo activity of quisinostat against Toxoplasma gondii PMID 40741955
由 cAMP 直接激活的交换蛋白
The KN Motif and Ankyrin Repeat Domains 1/CXXC Finger Protein 5 Axis Regulates Epithelial
GWP
Molybdenum facilitates PDLSC
Decorin impeded the advancement of thyroid papillary carcinoma by thwarting the EGFR/ FER/ SHP2 signaling
LXR and TSPO as new therapeutic targets to increase the levels of neuroactive steroids in the central nervous system of diabetic animals PMID 22406419
Dual Modes of Gene Regulation by CDK12 PMID 41040222
8
Androgen receptor variants confer castration resistance in prostate cancer by counteracting antiandrogen
Macrophages confer resistance to BET inhibition in triple
Osteogenic effect of crocin in human periodontal ligament stem cells via Wnt/β
Zenocutuzumab 1969309
Poziotinib suppresses ovarian cancer stem cell growth via inhibition of HER4
A novel role for YPEL2 in mediating endothelial cellular senescence via the p53/p21 pathway PMID 36963468
NKG2A 蛋白, Cynomolgus/Rhesus macaque (HEK293, His)
Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells PMID 23933481
PDE7
The Improving Effect of HL271, a Chemical Derivative of Metformin, a Popular Drug for Type II Diabetes Mellitus, on Aging
Balixafortide 1051366
Total Synthesis, Structure Reassignment, and Biological Evaluation of the Anti
N
MCE
Neuroprotective effect of pharmacological postconditioning on cerebral ischaemia
The active ingredient β
F2rl1 Rat Pre
Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric disease PMID 19367677
Prostanoid receptors and their biological actions PMID 8309950
SNAP
Preclinical characterization and IND
Activation of estrogen
MCE
SP
Empagliflozin reduces renal calcium oxalate deposition in hyperoxaluria rats induced with ethylene glycol
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy
A novel antagonist, phenylbenzene omega
Ixazomib Induces Apoptosis and Suppresses Proliferation in Esophageal Squamous Cell Carcinoma through Activation of the c
Tamarixetin Protects Chondrocytes against IL
Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells PMID 31485597
MKEY, a Peptide Inhibitor of CXCL4
UB
Biochemical routes for uptake and conversion of xylose by microorganisms PMID 32021652
Antidepressant activity of crocin
Inhibition of indoleamine 2,3
U
Polyvinyl alcohol (Mw 31000
CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule
Ca2+ channel agonist 1 1402821
Ikzf4
Discovery of [1,2,4]triazolo[1,5
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma PMID 35212145
A small population of stress
HMGCS1 drives drug
ABT
Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling PMID 32135457
Spike mutation D614G alters SARS
Oxiran
Tyrosine
Rational Design of a Potent Antimicrobial Peptide Based on the Active Region of a Gecko Cathelicidin PMID 38315114
18
Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide PMID 15215127
antiproliferative
What does elevated TARC/CCL17 expression tell us about eosinophilic disorders? PMID 34009399
D
(S)
GFRA3/GDNFR
The IL
Correlations among ERCC1, XPB, UBE2I, EGF, TAL2 and ILF3 revealed by gene signatures of histological subtypes of patients with epithelial ovarian cancer PMID 21971700
Ganoderic acid D 108340
(S)
Mislocalize
甲状腺激素受体相互作用物 6（TRIP6）基因
IgE 蛋白, Human (Biotinylated, HEK293, His
Girard's Reagent P
孕酮受体膜成分 2（PGRMC2）基因
A
Geldanamycin Reduces Acute Respiratory Distress Syndrome and Promotes the Survival of Mice Infected with the Highly Virulent H5N1 Influenza Virus PMID 28664154
Velagliflozin
HIF
(S)
MST1/STK4 蛋白, Human (His)
γ
9
Bimosiamose disodium 187269
Salvianolic acid A 96574
Ergothioneine exerts neuroprotective effects in Parkinson's disease Targeting α
Bcl
Csf2rb
Antitumor activity of CKD
Methyl ferulic acid exerts anti
IKZF1
PBEF
CD73
Bcl
Carbonate dehydratase
PROTAC JAK2 degrader
CD73
(2E,4E,6E)
Tnfrsf9 Rat Pre
The molecular basis for the selection of captopril cis and trans conformations by angiotensin I converting enzyme PMID 16889963
Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus PMID 27742832
[Nle20] H4 peptide (16−23)
Rucaparib camsylate 1327258
CSNK1A1
VUF
PET/CT imaging
First synthesis and biological evaluation of 4
Indusatumab 1497400
Yeast
Danofloxacin
ML
裂解刺激因子亚基 2（CSTF2）基因
Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration PMID 27535619
阿昔洛韦
EMD638683 R
C
Anti
SKF 106615
Cefcapene pivoxil hydrochloride (Standard)
Phospho
Aminooxy
Kynurenine
PROTAC SMARCA2/4
NOD
DNMTs
Identification and structural characterization of potential degraded impurities of ribociclib by time of flight
Pinusolide 31685
AVLX
IWP L6 1427782
Epidermin and gallidermin Staphylococcal lantibiotics PMID 24119540
[Effect of etimizol on instrumental learning in rats] PMID 4016262
An Anionic Cathelicidin Exerts Antimelanoma Effects in Mice by Promoting Pyroptosis PMID 40207383
Ganoderic acid C2 103773
Microneedle
Vanoxonin, a new inhibitor of thymidylate synthetase PMID 6874588
Flibanserin has anxiolytic effects without locomotor side effects in the infant rat ultrasonic vocalization model of anxiety PMID 10864879
HO
Inhibiting Stearoyl
RTICBM
Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti
Mechanical stretch
Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient
The Inhibitory Effects of Recombinant Hespintor Combined with Sorafenib on Transplanted Human Hepatoma in Nude Mice, and Transcriptional Regulation of Hespintor Based on RNA
Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro PMID 28766686
Thiostrepton Reactivates Latent HIV
Cryopreserved biopsy tissues of rectal cancer liver metastasis for assessment of anticancer drug response in vitro and in vivo PMID 31894341
Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL
NSUN2 inhibits NCOA4 expression to alleviate ferroptosis and inflammation in sepsis
Taurolithocholic Acid
A cell
Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 PMID 38228402
3,3',4,4'
N
A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain PMID 28457974
Liquiritigenin alleviates high
RS
Cyclic ADP
S100A7 Human Pre
REV
Feedback loop LINC00511
Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections PMID 7051761
HIV
Go6976
Effects of Maxingloushi decoction on immune inflammation and programmed death markers in mice with chronic obstructive pulmonary disease PMID 35003414
CGP7930 57717
Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma PMID 31431459
cAMP
Endothelin Receptor
GSK2033 1221277
Tryptophan catabolism is dysregulated in leiomyomas PMID 34116832
Tumor cell
Circular RNA CDR1
Diethanolamine hydrochloride (DEOA LF hydrochloride)
SCH
Local delivery of mesenchymal stem cell
Escherichia coli enhances Th17/Treg imbalance via TLR4/NF
DBCO
Phenolic thio
Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti
Sulfamethoxypyridazine
Multi
AP102 846569
Mal
Kinetin inhibits hepatic stellate cell activation and induces apoptosis via interactions with the TGF
Predicting HIV Pre
Myristyl nicotinate (Tetradecyl nicotinate)
MCE
A STING agonist potentiates C1 lipidoid
胰岛素样生长因子 2（IGF2）基因
Monomethyl kolavate
Synthesis and biological evaluation of N
DSPE
Novel TPO receptor agonist TA
Screening bioactive compounds from Danggui
1,3
蒙胃顿钠 (Standard)
Linoleyl carnitine
Overcoming BET Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors PMID 30796033
cereblon
10
Arteannuic alcohol (Amorpha
SB
Imiquimod hydrochloride 99011
Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish ( Danio rerio) PMID 32141807
liver
Antifungal agent 95
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer PMID 31857588
Valorisation of the diterpene podocarpic acid
Alfuzosin
Thiol
TB9
膜联蛋白 A11（ANXA11）基因
Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma PMID 31266951
AMPA receptor modulator
Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells PMID 33397092
Discovery of potential novel CRBN modulators by virtual screening and bioassay PMID 35413617
Spirulina
Investigating the potential role of α
ACSL4 deficiency confers protection against ferroptosis
Glucoraphenin potassium
Glutaminase
Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors PMID 15081875
Colchicine prevents NSAID
Cyclic GMP
Hydroxyzine dihydrochloride 2192
Estrogen Receptor/ERR
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