最近收录_第622页_生物活性分子
生物活性分子最近更新
RIP kinase
TBAJ
DDD85646 1215010
Circadian rhythms in toxic effects of the serotonin antagonist ondansetron in mice PMID 14680146
Primin 15121
RWJ270201
Sodium citrate dihydrate 6132
Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer PMID 38537775
Bempedoic acid 738606
An in vivo and in vitro model on the protective effect of cilnidipine on contrast
Idiopathic pulmonary fibrosis PMID 29052582
Catestatin
INX021
β
Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells PMID 37612272
SP1/CTR1
LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators PMID 34814071
Eliglustat hemitartrate
PTBP1
Garcinol promotes wound healing in diabetic mice by regulating inflammation and NLRP3 inflammasome
prototype
PL53
dihydrocodeinone
Dolastatin 10
Thalidomide
Thrombocytopenia PMID 24267279
Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf PMID 30795572
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF
SIRT1/PGC
Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide PMID 31563286
GTI
ANB 004
caspase
MK
Dendritic cell
Spectrum of bactericidal action of amylmetacresol/2,4
Lysine demethylase LSD1 delivered via small extracellular vesicles promotes gastric cancer cell stemness PMID 34060205
14
BI
C.I. Disperse blue 284
Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1
PROTAC EGFR degrader 10 3034244
OSBPL2 deficiency impaired cochlear blood
Mechanism of platelet
Ivacaftor, a CFTR potentiator, synergizes with osimertinib against acquired resistance to osimertinib in NSCLC by regulating CFTR
hay fever
aggregated amyloid β
N
Targeting IL
Heme oxygenase inhibition by 2
17β
Hexa
Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice PMID 28209760
GDC
New N
Pregabalin lactam (Standard) ((S)
MicroRNA
Arachidic acid
Tafluprost ethyl amide 1185851
LX 039
A phase I dose
CD40L/CD154/TRAP 蛋白, Human (Biotinylated, HEK293, His
3
Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors PMID 27502541
Heat
Copine
SBC
G protein
RNA
Carprofen
Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy PMID 12417742
6
TM7SF2
Uridine triphosphate trisodium salt 19817
(Rac)
130872
AZ'9567 3056570
GR
Sulfamethizole
DPQ hydrochloride 84050
Bilaid B1
[Cytotoxic effect of topoisomerase II inhibitors against adriamycin
A treatment algorithm for the management of chronic hepatitis B virus infection in the United States an update PMID 16844425
Pb Ag2Se QDs (Pb Ag2Se)
Beta adrenoceptor blocking properties of MK
Ischemic Microenvironment
Antitumor agent 156
CYP51 from Trypanosoma brucei is obtusifoliol
RANKL/TNFSF11 蛋白, Cynomolgus (HEK293, Fc)
Jak2 normal function and role in hematopoietic disorders PMID 17208428
Hepatitis B surface antigen hijacks TANK
MicroRNA
N
Hepatitis B Virus Infection Promotes M2 Polarization of Macrophages by Upregulating the Expression of B7x In Vivo and In Vitro PMID 36099202
A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery PMID 12531444
(S)
RBN
斑点型 BTB/POZ 蛋白样（SPOPL）基因
FKBP 脯氨酰异构酶家族成员 15（FKBP15）基因
Lumicitabine
84221
hSMG
KRAS G12C inhibitor 28 2649004
β
Functional activity of the adenosine binding enhancer, PD 81,723, in the in vitro hippocampal slice PMID 1817724
Silencing circular RNA
Comparative stereostructure
AcrAP1 (AP1
Beraprost sodium (Standard)
M2 macrophages promote vasculogenesis during retinal neovascularization by regulating bone marrow
RAGE mediates hippocampal pericyte responses and neurovascular unit lesions after TBI PMID 39097075
Disulfiram suppressed ethanol promoted RANKL
Basic yellow 28
Plasmid
Improved Efficacy of Triple
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines PMID 11985463
Regulating Nrf2
AN ALKYLATING AGENT FOR MULTIPLE MYELOMA MELPHALAN PMID 14239026
Role of phospholipases D1 and 2 in astroglial proliferation effects of specific inhibitors and genetic deletion PMID 25967349
The Discovery and Preclinical Profile of ALG
Toward a Microparticle
3
Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity PMID 35136056
A novel antagonist of TLR9 blocking all classes of immunostimulatory CpG
Acteoside
Antiviral agent 48 3032868
Gomisin D 60546
SHMT1 蛋白, Human (HEK293, His)
Enramycin
Leptin (116
Methyl
PEG 40 stearate
Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T
SARS
Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase PMID 11785983
(
Arphamenine B hemisulfate
Duloxetine 116539
Glycometabolism and lipid metabolism related genes predict the prognosis of endometrial carcinoma and their effects on tumor cells PMID 38720279
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGAS
Auditory Brainstem Deficits from Early Treatment with a CSF1R Inhibitor Largely Recover with Microglial Repopulation PMID 33558268
苄磺酰氟 (标准品)
Neuronal constitutive endolysosomal perforations enable α
Quercetin protects against iron overload
TIPE
Targeting of B and T lymphocyte associated (BTLA) prevents graft
Antifungal agent
Synthetic studies on novel benzimidazolopeptides with antimicrobial, cytotoxic and anthelmintic potential PMID 17239491
Violamine R 6252
Alisol B 23
A nature
CircGSK3B promotes RORA expression and suppresses gastric cancer progression through the prevention of EZH2 trans
Flg22
Apolipoprotein D is crucial for promoting perineural invasion in salivary adenoid cystic carcinoma PMID 39962257
Effective clearance of GL
Neuropilin
CD3D 蛋白, Human (HEK293, His)
茋三酚
Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79
Tmsb4x Mouse Pre
蛋白磷酸酶 6 催化亚基（PPP6C）基因
JNJ
SGS
[Phe8Ψ(CH
IMP
SJF
Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation PMID 17554144
trans
4
Obliterative airway disease
Thalidomide
Anti
AqF026
L 783279
E2F Transcription Factor 1 Activates FKBP Prolyl Isomerase 4 to Promote Angiogenesis in Cervical Squamous Cell Carcinoma Via the PI3K/AKT Signaling Pathway PMID 35849266
Cyclin dependent kinase
Amitriptyline (Standard)
cSSTI
PROTAC eDHFR Degrader
GSD
cardiovascular diseases and tissue repair
PLP2 Human Pre
NCT504
High
YM
MK
Coumarin sulfonamides derivatives as potent and selective COX
KRP
(1,5
GLPG3312
Molecular Insights of Copper Sulfate Exposure
ANB
他佐罗汀
Ago2
Use of 2,6
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein PMID 29256861
前列腺素 F2a
RBM1
Palmitoylethanolamide
High energy focused ultrasound
Caveolin
JTT553
Acetylformic acid (Standard)
2
NIBR
YU
AF45
Gostatin
High throughput screens identify genotype
MicroRNA miR
Chemoproteomic strategy identifies PfUCHL3 as the target of halofuginone PMID 38923255
Tianeptine
human colorectal and cervical carcinoma
Propionibacterium acnes induces discogenic low back pain via stimulating nucleus pulposus cells to secrete pro
CD274
GKT136901 protects primary human brain microvascular endothelial cells against methamphetamine
L
glucosyl
The impact of short
Deleting fibroblast growth factor 2 in macrophages aggravates septic acute lung injury by increasing M1 polarization and inflammatory cytokine secretion PMID 39436561
Killing of intraleukocytic Staphylococcus aureus by rifampin in
TNF
SK 1403
chondrocyte
mRNA drug delivery
Reduction of primordial follicles caused by maternal treatment with busulfan promotes endometrial adenocarcinoma development in donryu rats PMID 16177545
Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma PMID 35875091
IL
Design, synthesis and photochemical properties of the first examples of iminosugar clusters based on fluorescent cores PMID 26124868
Chemical Analysis and Antidiabetic Potential of a Decoction from Stevia serrata Roots PMID 37738100
Tetrahedral Framework Nucleic Acids Promote Corneal Epithelial Wound Healing in Vitro and in Vivo PMID 31192537
Enhanced efficacy of gemcitabine by indole
Molecular and conformational determinants of pituitary adenylate cyclase
3
Practical management of boceprevir and immunosuppressive therapy in liver transplant recipients with hepatitis C virus recurrence PMID 22908172
Astragaloside and/or Hydroxysafflor Yellow A Attenuates Oxygen
ido
First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma PMID 23727874
小苏打, 用于分子生物学
LY 3009104
2,3,7,8
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target PMID 40488834
Tat
[8]
ZLY06 2834727
Niraparib tosylate 1038915
4
沃替西汀
A fluorogenic cyclic peptide for imaging and quantification of drug
HS
Circular RNA has circ 0001591 promoted cell proliferation and metastasis of human melanoma via ROCK1/PI3K/AKT by targeting miR
(
Antioxidant activity of fresh and processed Jalapeño and Serrano peppers PMID 21126003
Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models PMID 1696656
The opposite effect of ELP4 and ZEB2 on TCF7L2
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5
Magnesium sulfate
Ro4368554
HBX 41108
PARPs
2'
Z52
ACES (N
丙糖磷酸异构酶 1（TPI1）基因
IdeS protease
Win 47338
Identification of Novel Modulators of the ALT Pathway Through a Native FISH
HCoV
Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells PMID 35806457
Opposite physiological and pathological mTORC1
Cyproterone acetate enhances TRAIL
Discovery of 6
Fine Particulate Matter (PM2.5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway PMID 30305224
Benzyl
F2R 样胰蛋白酶受体 1（F2RL1）基因
Cardiometabolic Modulation by Semaglutide Contributes to Cardioprotection in Rats with Myocardial Infarction PMID 39640291
Overexpression of Foxc1 ameliorates sepsis‑associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF‑κB pathway PMID 35103290
Tazarotene (Standard)
A fatty acyl
Lgals3
Maternal behavior promotes resilience to adolescent stress in mice through a microglia
N
Hnrnpa2b1 Rat Pre
Targeting 7
GAK a cyclin G associated kinase contains a tensin/auxilin
Adsorption of anti
Managlinat dialanetil, a fructose
Induction of CTL responses and identification of a novel epitope of hepatitis B virus surface antigens in C57BL/6 mice immunized with recombinant vaccinia viruses PMID 11163641
BMP4 initiates human embryonic stem cell differentiation to trophoblast PMID 12426580
Phenylsulfate
KIR2DL4 promotes the proliferation of RCC cell associated with PI3K/Akt signaling activation PMID 35063466
CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue PMID 31715371
Enhanced Photodynamic Therapy Synergizing with Inhibition of Tumor Neutrophil Ferroptosis Boosts Anti
(24R)
Targeting ROS
Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth PMID 38317232
NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma PMID 32579914
IMP2
Formosanin C induces autophagy
C14 Benzalkonium
Pharmacological Inhibition of Phosphoglycerate Kinase 1 Reduces OxiDative Stress and Restores Impaired Autophagy in Experimental Acute Pancreatitis PMID 39470963
TNF 受体超家族成员 14（TNFRSF14）基因
Sulfiredoxin 1 ameliorates doxorubicin
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression PMID 40445264
盐酸西那卡塞(Standard)
Gastric cancer
TCAP Human Pre
Discovery of natural product
Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer PMID 23403296
MAP4K
2& 039;
Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment PMID 23766363
Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis PMID 22286157
ALC
1(R)
ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia PMID 35247902
(d(CH2)51,Tyr(Me)2,Orn8)
MEGA
Ipatasertib
Selective non
Methylcobalamin
2
Shen
PTEN inhibitor VO
Flufenoxuron
Hexanenitrile (Capronitrile，己腈)
5
A Sex
3(S)
核糖体蛋白 S6 激酶 A3（RPS6KA3）基因
The mechanism of Shenlong Jianji treatment of idiopathic pulmonary fibrosis inhibits fibroblast
Tropomyosin related kinase receptor
Bacitracin 1405
连接蛋白细胞粘附分子 4（NECTIN4）基因
Amino
Role of ADAM33 short isoform as a tumor suppressor in the pathogenesis of thyroid cancer via oncogenic function disruption of full
Involvement of the P2X7 receptor in the migration and metastasis of tamoxifen
HCLS1 相关蛋白 X
Riltovetbart 2641479
MK
具有 kazal 基序的逆转诱导富半胱氨酸的蛋白质（RECK）基因
乙型肝炎病毒相关肝细胞癌 (Hepatitis B Virus Related Hepatocellular Carcinoma)
A dual
Zn2+ regulates mitochondrial DNA efflux to inhibit AIM2
The effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responses to neurokinin A in normal humans in vivo PMID 1317691
Kifc3 Mouse Pre
H
H2L 5765834
Mometasone furoate 83919
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia PMID 32908143
Bencaosome [16 0 Lyso PA+XLGB28
Cathepsin inhibitor 1 225120
MEK inhibition prevents human skin graft rejection by promoting CD8+TCF1+ over CD8 effector T cells PMID 40894910
LGALS3BP is a potential target of antibody
SK
Oroxylin A
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein
The aryl hydrocarbon receptor affects the inflammatory response of bone marrow mesenchymal stem cell via the hippo
Effect of alkyl chain length, head group and nature of the surfactant on the hydrolysis of 1,3
ABBV383
Versatile Protein Coronation Approach with Multiple Depleted Serum for Creating Biocompatible, Precision Nanomedicine PMID 35775952
Splenic B cell
MiR
BT
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress PMID 31212751
SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia PMID 38517966
Benfotiamine, a Lipid
CCN5 negatively regulates TGF
Thromboxane B2
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma PMID 34720024
Substituted indole derivatives as UNC
Structural characterization and macrophage activation of a hetero
跨膜蛋白 182（TMEM182）基因
Anti
Effect of mono
Oscillamide C TFA
Effects of stachydrine on norepinephrine
Aβ
D
生化试剂
ALT
Enhanced anti
TMEM45A Affects Proliferation, Apoptosis, Epithelial
Tripentadecanoin
Adam23
complement activation
Methyl 4
UniPR129 is a competitive small molecule Eph
Regiospecific microwave
Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression PMID 36042351
Distribution, phenotype, functional and clinical relevance of CD8+CD103+ tissue
Prevalence and Mechanisms of Mucus Accumulation in COVID
NU9056 1450644
Epigallocatechin 3
BMP15 regulates AMH expression via the p38 MAPK pathway in granulosa cells from goat PMID 29885643
AGN 191976 159359
Pan
TFAM 蛋白, Human (His)
Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor
The novel role of activating receptor KIR2DS5 in preeclampsia PMID 37864908
SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway PMID 26097571
Therapeutic potential of metabotropic glutamate receptor 4
16 0
Alpha
Riselcaftor 2799652
BITC and S
DNA Stain
Whey protein hydrolysate alleviated acetaminophen
MCE
Novel hybrid conjugates with dual estrogen receptor α degradation and histone deacetylase inhibitory activities for breast cancer therapy PMID 33965842
Nilvadipine
PF
Gastrin receptor antagonist CI
Hydroxy
CU
zVAD alleviates experimental autoimmune hepatitis in mice by increasing the sensitivity of macrophage to TNFR1
Structural and Functional Analysis of the D614G SARS
Penttinen syndrome
Acylhydrazone derivatives as potential anticancer agents Synthesis, bio
Identification and Experimental Verification of PDK4 as a Potential Biomarker for Diagnosis and Treatment in Rheumatoid Arthritis PMID 39466354
MCE
Isolongifolene 1135
Adaptor protein complex 1 gamma 1 subunit is an important host factor involved in both Zika virus and dengue virus infections PMID 40759332
TRIM8 promotes ovarian cancer proliferation and migration by targeting VDAC2 for ubiquitination and degradation PMID 38881325
Amine
5
Cetylamine
Role of increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development A pilot study PMID 38316422
Mechanistic and target study of anthraquinone modifier KA
Resistance to the KRASG12D Inhibitor MRTX1133 is Associated with Increased Sensitivity to BET Inhibition PMID 40463163
Synthesis, structure
Diclosulam 145701
Gallein increases the fibroblast growth factor 2
Clinical Efficacy and Safety of Baminercept, a Lymphotoxin β Receptor Fusion Protein, in Primary Sjögren's Syndrome Results From a Phase II Randomized, Double
5
LAIR
Synthesis and in vitro anti
KRIBB11 342639
Cytotoxic CD8+ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma that Drives Antitumor Immunity PMID 40828991
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis PMID 33441552
Modulation of G6PD affects bladder cancer via ROS accumulation and the AKT pathway in vitro PMID 30066842
R162 64302
GSK3787 188591
OICR11029
Electroacupuncture reduces microglial pyroptosis via P2X7R/NLRP3 axis in the rat model of asphyxial cardiac arrest and cardiopulmonary resuscitation PMID 39952315
Specnuezhenide attenuates rheumatoid arthritis bone destruction via dual regulation of osteoclast
C
The SPPL3
Complement c5a receptor facilitates cancer metastasis by altering T
Butyrolactone 3 778649
The sodium phosphate cotransporter family SLC34 PMID 12750889
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts PMID 30649212
A metabolic switch orchestrated by IL
Rice ragged stunt virus Pns10 induces mitochondrial
Salmonella exploits LRRK2
Effects of alendronate and taxol on PC
Cdkn1c
Small intestinal glucose and sodium absorption through calcium
MCE
Etalocib 161172
The microglial innate immune receptors TREM
Synthesis and biological activity of enantiomeric pairs of 5
Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF
A3AR antagonist 2 1144161
Single
Jun Mouse Pre
The volume regulated anion channel VRAC regulates NLRP3 inflammasome by modulating itaconate efflux and mitochondria function PMID 38006980
Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response PMID 40914169
Hexidium iodide 211566
A Non
Ultrafast Intramolecular Proton Transfer of Alizarin Investigated by Femtosecond Stimulated Raman Spectroscopy PMID 28375609
Integrating network toxicology, transcriptomics, and metabolomics uncovers the hepatotoxic mechanisms of okadaic acid in LO2 cells PMID 40561608
Integrated UHPLC
Site
Anisaldehyde and Veratraldehyde Acting as Redox Cycling Agents for H(2)O(2) Production by Pleurotus eryngii PMID 16349349
Sec10 suppresses antiviral innate immune response by facilitating STUB1
Harnessing DSB repair to promote efficient homology
Pyrrolo[3,2
Activin receptor
Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes PMID 30528696
(Rac)
Boc
RuBi
The immune checkpoint receptor LAG3 Structure, function, and target for cancer immunotherapy PMID 38556085
Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995
Chd6
Tacrolimus reverses pemphigus vulgaris serum
I
Effect of catalysis on the stability of metallic nanoparticles Suzuki reaction catalyzed by PVP
Synthetic flavagline derivative 1
Mesenchymal stem cells alleviate idiopathic pneumonia syndrome by facilitating M2 polarization via CCL2/CCR2 axis and further inducing formation of regulatory CCR2 + CD4 + T cells PMID 40025564
Bisoprolol reverses epinephrine
The angiosuppressive effects of 20(R)
MES monohydrate 145224
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality PMID 21813754
Trans
GTP 结合蛋白在骨骼肌中过表达（GEM）基因
6
Retinoic Acid Receptor Agonists Suppress Muscle Fatty Infiltration in Mice PMID 33428447
(S)
共652页
首页
上一页
627
626
625
624
623
622
621
620
619
618
617
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新