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N6
3’
Differential modulation of retinal ganglion cell light responses by orthosteric and allosteric metabotropic glutamate receptor 8 compounds PMID 23164615
BDM91288
DOTA
Valproic acid overcomes sorafenib resistance by reducing the migration of Jagged2
Antitrypanosomal agent 5
Nitric oxide synthesis
Protamine Sulfate Neutralization Profile of Various Dosages of Bovine, Ovine and Porcine UFHs and Their Depolymerized Derivatives in Non
Investigation on the chemical space of the substituted triazole thio
OTP Human Pre
Nutlin
High expression of CX3CL1/CX3CR1 at the mother
MGS1
15
O
Hypidone hydrochloride (YL
WK499
Anticancer agent 280
Mollicellin I
10
Synthesis and evaluation of anticancer activity of some novel 6
Effects of gefitinib treatment on cellular uptake of extracellular vesicles in EGFR
补体 C3d 受体 2(CR2)基因
MC 976
2,2',4,4'
Lefleuganan
Ouabagenin 508
2
[Studies on residual antimalarial activity of tripynadine in mice and monkeys] PMID 8168241
MCE
BP 554
ASCT2
IMU
ChIP
The antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction PMID 40475483
SCIO469
TRPA1 protects against contrast
N3
Lobendazole
Cortisol sulfate (Cortisol 21
TNF
Targeting Ferroptosis by Polydopamine Nanoparticles Protects Heart against Ischemia/Reperfusion Injury PMID 34730938
DNDI
Srcin1
3
S18327 200398
Mitochondria
Chloramultilide B 1000995
Involvement of mitochondrial fatty acid β
Lucanthone N
Cyclic GMP analogs inhibit gamma thrombin
(R)
(E)
Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4
KW
Long non
CA224
MCE
Hydroxy
MRS4917
Short
Cep76
A systematic evaluation of protein kinase A
M
溶质载体家族 22 成员 6(SLC22A6)基因
MuRF1
RI
CGP 28392 89289
Manumycin F 156317
OP
Diethyl 4
Preclinical Pharmacokinetics and Biodistribution Studies of 89Zr
IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling PMID 30816520
Ardisianone 66398
Tubercidin 5'
跨膜蛋白 17(TMEM17)基因
(1
2
Sucrosofate potassium 73264
BDP 650/665 X NHS ester
FZ1 peptide
ADAMDEC1 蛋白, Human (HEK293, His)
23473
Furalaxyl 57646
neutropenic
TH
Effective compound combination of Bufei Yishen formula ameliorates PM2.5
NHS
Tixanox sodium 40691
BMS
7
D
DDB
(R)
Dendrobine attenuates sepsis
RUNX 家族转录因子 1(RUNX1)基因
Bioenergetic effects of mitochondrial
RP
LF3 (Standard)
Deacetyldiltiazem 42399
Methyl 12
Homobrassinolide 74174
辛伐他汀羟酸
Δ9
GF
FCAR/CD89 蛋白, Human (HEK293, His)
LARP4B Human Pre
Inhibition of hemangioma development by regulating the VEGF/VEGFR autocrine loop via the miR
Allicin alleviates traumatic brain injury
Design, Synthesis, and Characterization of TNP
Rnf2 Mouse Pre
Pancreatic cancer
Lysosomal membrane permeabilization mediated apoptosis involve in perphenazine
PF
含 valosin 的蛋白相互作用蛋白 1(VCPIP1)基因
Ethyl 2
Synthesis and properties of a selective inhibitor of homeodomain
2
Alniditan 152317
NLRP3 inflammasome
Ticagrelor acetonide (Isopropylidene ticagrelor)
NCI126224 65974
Bagremycin B 93316
Anti
MCE
USP1
Apln
Cynarin 30964
Eperisone Hydrochloride, a Muscle Relaxant, Is a Potent P2X7 Receptor Antagonist PMID 38556262
N
Actions of nizatidine, a selective histamine H2
Ilurodoline impurity 10
Pre
MCE
JNJ16259685
Tris(2
Pharmacological effects and mechanism of Ilexsaponin A1 in modulating platelet function PMID 40015536
2
(S)
AZD
CAM4066
Ginsenoside Rg1 inhibits angiogenesis in diabetic retinopathy through the miR
Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B PMID 40390212
MTPPA 70991
Bromo
N
Chn1
N,N,N',N'
MDA
Methyl cis
BCL6 转录抑制因子(BCL6)基因
Examining the binding properties of MK
Aminoflavone (NSC
MCE
Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1 PMID 39497419
Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α
CypHer 5 (solution)
The prolyl isomerase PIN1 a pivotal new twist in phosphorylation signalling and disease PMID 17878917
FM4
MCE
Mitoguardin
Isoremoxipride
Novel promising 4
AT
(2R,3R)
Justicidin A 25001
Zhebeirine 143120
BTLA/CD272 蛋白, Rat (HEK293, mFc)
Activin receptor
HGF
溶质载体家族 16 成员 7(Slc16a7)基因
steroidogenic
1
Lenalidomide
TNF 超家族成员 12(TNFSF12)基因
DMT
MCE
trans
Obesity and its comorbidities, current treatment options and future perspectives Challenging bariatric surgery? PMID 37879540
Repression of the Type I Interferon Pathway Underlies MYC
7
3
Temocapril treatment ameliorates autoimmune myocarditis associated with enhanced cardiomyocyte thioredoxin expression PMID 12123771
Glycyrrhetinic Acid as a Hepatocyte Targeting Ligand
VHR
Mapenterol hydrochloride
ME 2303 (FAD 104)
磷酸二酯酶 9A(PDE9A)基因
BO 1341
Celsr2
Bisnoralcohol 40736
LK 204
PIN1 degrader
Boc
Acetylation Blocks cGAS Activity and Inhibits Self
Protective effect of Enterococcus faecium against ethanol
SIRT2
MCE
TP
Taurocholic acid 3
LP 935509
3
Abl
Identification of novel cyclooxygenase
MiR
Farnesylthioacetic acid
VP
3
PF
Global expression response of genes in sex
Anticancer agent 285
Characterization and inhibition of a cholecystokinin
CD3D
PROTAC BET
Phosphoramidon 36357
LLL3 (CLT
C527
Acid
Targeting a key disulfide linkage to regulate RIG
Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity PMID 30275542
Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)
Inflammation
Regulatory mechanism of perinatal nonylphenol exposure on cardiac mitochondrial autophagy and the PINK1/Parkin signaling pathway in male offspring rats PMID 38367424
Hexoprenaline
Pharmacokinetic profile of Mitoguazone (MGBG) in patients with AIDS related non
hsa
DORA
Near
Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice PMID 29212208
Resveratrol analog 1 861446
Bisphenol P
Hepatitis B virus
Nanospheres loaded with curcumin promote gut epithelial motility through F
Neoaspergillic acid 2152
HCT
SnapShot Interferon Signaling PMID 26687364
Hexavalent chromium disrupts the skin barrier by targeting ROS
GABABR
Isostearic acid 2724
Apoptosis inducer24
IL
USP4 promotes PTC progression by stabilizing LDHA and activating the MAPK and AKT signaling pathway PMID 39393052
Genome
MCE
Modulation of TLR9 response in a mouse model of herpes simplex virus encephalitis PMID 23043942
Silencing of long non‑coding RNA HRIM protects against myocardial ischemia/reperfusion injury via inhibition of NF‑κB signaling PMID 33174008
2
MCE
(S)
CRIPT
Antidiabetic and antioxidant potential of β
(rel)
Ziyuglycoside II inhibits the growth of human breast carcinoma MDA
TP
Raloxifene 6
Genetic variation drives cancer cell adaptation to ECM stiffness PMID 39302966
Ataluren 775304
MCE
Fluorobenzene
LCZ960 1067877
Regaloside D
ELA
Arnolol 87129
RX 336M
Hypothalamic localization of the feeding effect of agouti
杀伤细胞凝集素样受体 B1(KLRB1)基因
2',6'
Methyl 7,15
Nerve growth factor enhances the CRE
SARS
NIM258
MCE
2
Phthalimidylbenzenesulfonyl chloride
(Z)
TRAILR4/TNFRSF10D 蛋白, Human (HEK293, His)
Ptbp1 Rat Pre
OAT
Ag2S
Estragole DNA adduct formation in primary rat hepatocytes and genotoxic potential in HepG2
Chikungunya virus infection molecular biology, clinical characteristics, and epidemiology in Asian countries PMID 34857000
A Novel Cryptococcal Meningitis Therapy The Combination of Amphotericin B and Posaconazole Promotes the Distribution of Amphotericin B in the Brain Tissue PMID 33313322
Gö6983 attenuates titanium particle
D
Dinalbuphine sebacate (Sebacoyldinalbuphine)
NM23A 抗体 (YA1003)(NM23A Antibody (YA1003))
FGFR
UNC569 1350547
Pancuronium dibromide 15500
CD69 分子(CD69)基因
PF
溶质载体家族 25 成员 1(SLC25A1)基因
(S)
BJH
CHO
PDPN+LTBP1+ cancer
2,3
APC 抗体 (YA617)(APC Antibody (YA617))
Dual Nicotinamide Phosphoribosyltransferase (NAMPT) and Indoleamine 2,3
Regorafenib Hydrochloride 835621
Mal
Nerve growth factor promotes the proliferation of Müller cells co
DAA
Methyl 4
The Antagonist of Retinoic Acid Receptor α, ER
两面神激酶 1(JAK1)基因
RAD51 重组酶(RAD51)基因
Trypanothione TFA
Lys05 1391426
5
Cholesterol Dehydrogenase, Nocardia sp. 67775
Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release PMID 25733887
An enoyl
CCG215022
LB
Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer PMID 29295954
[Arg14,Lys15]Nociceptin TFA
Melitracen
MRL
PAD
MARCKS N
Overcoming high level adenosine
(±)
Targeting PPARγ via SIAH1/2
Recombinant human adiponectin as a potential protein for treating diabetic tendinopathy promotes tenocyte progenitor cells proliferation and tenogenic differentiation in vitro PMID 24324367
Mefloquine hydrochloride 51773
Mathemycin B 233262
(±)
15
Roles of E2F family members in the diagnosis and prognosis of head and neck squamous cell carcinoma PMID 36855110
Dietary supplementation of Lactobacillus casei alleviates permethrin exposure
Up
BI
disk diffusion
Identification of Sinigrin as Active Compound of Rape Pollen for Treating Benign Prostatic Hyperplasia Through PI3K/AKT/mTOR Axis PMID 40343383
caspase
Antiplasmodial Alkaloids from the Australian Bryozoan Amathia lamourouxi PMID 33105995
Placenta
MCE
AZD
Pecavaptan 1914998
Physalin B
Oleoylethanolamide
Fc 受体样 6(FCRL6)基因
CTP 合成酶 1(CTPS1)基因
Targeting ATR in vivo using the novel inhibitor VE
Syringaldehyde Ameliorates Cognitive Dysfunction in APP/PS1 Mice by Stabilizing the NLRP3 Pathway PMID 40711709
dCTPase
Determining sex differences in aortic valve myofibroblast responses to drug combinations identified using a digital medicine platform PMID 40479052
甘油酸激酶(GLYCTK)基因
Modelling the impact of JNJ
Cepharanthine induces apoptosis through reactive oxygen species and mitochondrial dysfunction in human non
radiation
AKAP1/PKA
Understanding the mechanism of action of pyrrolo[3,2
II 型跨膜丝氨酸蛋白酶
HMGB1
Role of deubiquitinase USP47 in cardiac function alleviation and anti
OPN
含伴侣蛋白的 TCP1 亚基 3(CCT3)基因
HSD17B13
4
Calcium Influx An Essential Process by which α
Ac
Effects of Catecholamine Metabolites on Beta
Indolidan (LY195115)
Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice PMID 32625168
Unveiling the Therapeutic Potential of Banxia Xiexin Decoction in Alzheimer's Disease Insights From Network Pharmacology and Experimental Validation PMID 40134954
Effect of cyproterone acetate on the structure of the adrenal cortex PMID 485632
Discovery of (R)
Discovery of Imidazo[1,2
Phospholipase D A new mediator during high phosphate
Non
A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats PMID 17203197
Spiranthesol 125263
The in vitro estrogenic activities of triclosan and triclocarban PMID 24740835
MCE
ZFYVE16 Human Pre
USP10 promotes the progression and attenuates gemcitabine chemotherapy sensitivity via stabilizing PLK1 in PDAC PMID 40517136
Somatic PIK3R1 mutations in the iSH2 domain are accessible to PI3Kα inhibition PMID 40389643
SGLT2 inhibitors PMID 26362302
Region
Dnmt3a
Adenine riboside
MAP kinase kinase kinase
Antiviral activity and inhibition of topoisomerase by ofloxacin, a new quinolone derivative PMID 2827566
Sortilin antagonist1
Disruption of XIAP
Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels PMID 19228959
9
Levobupivacaine hydrochloride 27262
PCSK9 promotes progression of anaplastic thyroid cancer through E
丝裂原激活蛋白激酶
CHD1L augments autophagy
Synthesis, in silico, in vitro, and in vivo investigation of 5
Novel acridine
Hypromellose (Type II,Viscosity 100000mPa.s)
Tau
Glycidamide
钙电压门控通道辅助亚基 β 3(CACNB3)基因
Mouse IgG2c kappa, Isotype Control
Cyclosporin H, Boc
Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo PMID 24288293
Xylopine 517
GTF2IRD2
[Inhibitory effects of protein kinase C inhibitors on tumor necrosis factor induced bovine pulmonary artery endothelial cell injuries] PMID 9206266
Hippocampal astrocyte dysfunction contributes to etomidate
Antioxidants L
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer PMID 32483383
Quercetin 117
磺醋酰胺钠
Standard operating procedures in experimental liver research thioacetamide model in mice and rats PMID 25835735
Fast assembly of 'clickable nanogels' for drug delivery PMID 40786133
CDK4/6
DprE1
Arginase
Salmeterol 89365
DGK
anti
CD30 Ligand/TNFSF8 蛋白, Human (HEK293)
CC
Erythromycin thiocyanate (Standard) (红霉素硫氰酸盐 (Standard))
TBAJ
(Rac)
甲氧苄啶
ROR
(S)
SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes PMID 40531618
Assessment of drug
MCE
PD
Identification of molecular subtypes based on bile acid metabolism in cholangiocarcinoma PMID 39455933
比卡鲁胺(Standard)
P300
Combining Smoothened Agonist and NEL
Paeoniflorin protects against cisplatin
MP
Treatment of ear, nose and throat infections with clofoctol PMID 3915468
Esenbeckia leiocarpa,alkaloid
Navitoclax (ABT
4,5
PROTAC
Elagolix sodium 832720
Fenbendazole
Amorphous solid dispersions of hecogenin acetate using different polymers for enhancement of solubility and improvement of anti
Dual Inhibition of IGF
Cetrorelix diacetate
L
8
Iodoethane
Aberrant activation of the PI3K/AKT/HIF‑1α pathway promotes glycolysis and lenvatinib resistance in liver cancer PMID 40878941
SENP1 promotes p27kip1 nuclear export though enhanced SUMOylation in cholangiocarcinoma leading to increased cell proliferation and chemoresistance PMID 40682835
PCSK9
TLR8 antagonist
Hemicholinium 3 312
KR
4
Z
CXCR2
MK
Inositol hexaphosphate dodecasodium
Neuronal growth patterns and synapse formation are mediated by distinct activity
Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia PMID 26165234
PARP14 inhibits microglial activation via NNT to alleviate depressive
SKI
High FAAP24 expression reveals poor prognosis and an immunosuppressive microenvironment shaping in AML PMID 37328842
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient PMID 30692685
Treatment of myoclonus with L
含富亮氨酸的重复和无菌 alpha 基序 1(LRSAM1)基因
Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase
Improving the function of meningeal lymphatic vessels to promote brain edema absorption after TBI PMID 36106596
Pyrimethamine (Standard)
LAIR1 蛋白, Human (Biotinylated, HEK293, His)
3,3',5,5'
Halofantrine Hydrochloride Acts as an Antioxidant Ability Inhibitor That Enhances Oxidative Stress Damage to Candida albicans PMID 38397821
Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway PMID 30071202
S
Asiaticoside protected brain injury in hypertensive intracerebral hemorrhage via activation of the PI3K/AKT pathway PMID 39253885
[Dobutamine mechanisms of action and use in acute cardiovascular pathology] PMID 1859148
Gestodene 60282
rel
1
Evenamide 1092977
cis
Enterolactone 78473
Antiepileptic C21 steroids from the roots of Cynanchum otophyllum PMID 25579837
Omicron SARS
Furosemide sodium (Standard)
日本厚朴提取物 (Houpoea obovata (Thunberg) N. H. Xia & C. Y. Wu)
Hydroxytyrosol Reprograms the Tumor Microenvironment in 3D Melanoma Models by Suppressing ERBB Family and Kinase Pathways PMID 40725203
The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats PMID 26415531
PTI
Frizzled
Nelistotug 2645437
Anti
Lanepitant 170566
Route
PSMA
Integrated transcriptomics and network pharmacology to reveal the mechanism of Physochlainae Radix in the treatment of asthma PMID 39947003
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