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Mbd4
Sodium sulfate decahydrate
NLG802
Mtdh Mouse Pre
MCE
FAD
Lexaptepid Pegol (NOX
MCE
LtaS
Itga8 Rat Pre
Nrf2 ligand
Tyramine oxidase, Microorganism (酪胺氧化酶,微生物)
MCE
MCE
St6galnac4 Mouse Pre
MCE
MCE
Trimethadione 127
MRTX849 analog 24
MCE
13(R)
Bromoxynil octanoate 1689
蛋白酶体 26S 亚基,ATPase 2(PSMC2)基因
IP3R1 regulates Ca2+ transport and pyroptosis through the NLRP3/Caspase
CDK9 inhibition activates innate immune response through viral mimicry PMID 38661032
Azido
KI
Butorphanol Promotes Macrophage Phenotypic Transition to Inhibit Inflammatory Lung Injury via κ Receptors PMID 34305926
MCE
Ecabet sodium (TA
2
ACVR1 蛋白, Mouse (HEK293, His
MCE
HDAC
SMARCA1 Human Pre
DC
3
KRAS G12C inhibitor 22
CDRI
Eif2a Mouse Pre
SLC25A1 Human Pre
Etalocib (LY293111)
MCE
MCE
MCE
N
Downregulation of connexin 43
Flavokawain A is a natural inhibitor of PRMT5 in bladder cancer PMID 36199122
LIJTF500025 2838087
ALX 同源框 1(ALX1)基因
Deoxycholic acid disulfate sodium 71387
(S)
Acivicin 42228
3’
huATN
Adora1 Rat Pre
Junb Rat Pre
2
High
Nudifloramide
Nifursol
MCE
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis PMID 38142586
Kpna1 Mouse Pre
E3 ligase Ligand 76
Anti
o
The SFTSV Nonstructural Proteins Induce Autophagy to Promote Viral Replication via Interaction with Vimentin PMID 37039677
MCE
MCE
BAY1021189
Lair1
CEP
IHCH
线粒体编码的 ATP 合酶 8(MT
Deletion of Smooth Muscle Lethal Giant Larvae 1 Promotes Neointimal Hyperplasia in Mice PMID 35140622
Antimalarial agent 53
HDAC6
Hexyl gallate (Hexyl 3,4,5
NEU2 蛋白, Human (HEK293, His)
HDAC
KRASG12C IN
Cephalomannine inhibits hypoxia
KPNA1 Human Pre
Telaglenastat
VH 101 phenol
YK
Retinoic Acid Receptor alpha 抗体 (YA096)(Retinoic Acid Receptor alpha Antibody (YA096))
HDAC
Z
SLAMF1 Human Pre
Arpc3 Rat Pre
DEPN
MCE
无远端同源异源盒 3(DLX3)基因
Dihydroxy melphatalan 72143
Methotrexate metabolite 19741
MC
M084 51314
Hepatocyte cellular repressor of E1A
KRAS G12D
AChE
ATP1B4 Human Pre
Arisanlactone D 1234186
Methyl tricosanoate (Standard)
MCE
SRY
2
4
MCE
MCE
Clenbuterol hydrochloride 21898
MCE
KRAS G12C inhibitor 40
Role of hydroperoxyeicosatetraenoic acids in oxidative stress
N
Artefenomel (Standard)
MCE
4
复合物质谱研究
Withanolides from dietary tomatillo suppress HT1080 cancer cell growth by targeting mutant IDH1 PMID 33735687
Fmoc
Picloxydine 5636
CK2 inhibitor 3
4’
Anidoxime hydrochloride 31729
CBK289001
Nfatc1 Mouse Pre
CPB1 Human Pre
S100A8
MCE
Human ectodermal organoids reveal the cellular origin of DiGeorge Syndrome PMID 40855884
KRas G12R inhibitor 1
Zndm19
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis PMID 7997261
ULK
MCE
Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone PMID 22182595
Cardiomyocyte Targeting Peptide to Deliver Amiodarone PMID 37214919
KRAS inhibitor
Cyclo(GRGDSPA)
MCE
Sulfo
Biomimetic organo
MCE
Leukotriene B3 88099
Arabinose
6
β
KRAS G12C inhibitor 29
KRAS G12C inhibitor 37
MCE
HDAC6
MCE
KRAS
Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signals PMID 38159379
LncRNA AFAP1
Mechanical stress protects against chondrocyte pyroptosis through TGF
ML396
4
Tomopenem 222400
Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP
MCE
3,5
Roxatidine acetate 78628
Mitochondria
Necroptosis Mediates Cigarette Smoke
Experiments on an early protection against foot
Orchestrated desaturation reprogramming from stearoyl
Antibiotic PF 1052
Uncovering the pharmacology of the G protein
Effect of a novel potent platelet
Anti
Polr1b Mouse Pre
KRAS G12C inhibitor 20
2
KRAS G12V Peptide TFA
17
Sp
MCE
Rosiglitazone attenuates Acute Kidney Injury from hepatic ischemia
MCE
D
GDF15 is a major determinant of ketogenic diet
Quality by design
Viniferol D (葡萄醇D)
PROTAC HDAC6 degrader 7
NODAGA
MCE
Cryptotanshinone promotes brown fat activity by AMPK activation to inhibit obesity PMID 39109201
4
TMEFF1 Human Pre
Acadesine alleviates acute pancreatitis
Omigapil maleate (CGP3466B)
Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits PMID 32781905
(D
2,6
Methyl picolinate 2459
Quercetin liposomes conjugated with hyaluronidase An efficient drug delivery system to block pancreatic cancer PMID 40127723
OJT008
mmu
MAO
MCE
Tos
KRAS
RNASEH2A Human Pre
MCE
EIF2S1 Human Pre
MCE
CRBN ligand
HDAC10
Nudifloramide 701
Negative feedback loop of ERK/CREB/miR
核受体共激活因子 3(NCOA3)基因
MCE
(E,E)
(+)
MCE
HDAC6
DHFR
ARPC3 Human Pre
YSR734
Arabinose
Activation of RAW264.7 macrophage by Exopolysaccharide from Aphanothece halaphytica (EPSAH) and the underlying mechanisms PMID 32083746
P32/98 136259
Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance PMID 26202014
CP
JunB 抗体 (YA325)(JunB Antibody (YA325))
3,5,6
真核翻译起始因子 3 亚基 A(EIF3A)基因
HSP90
Diazinon
A Highly Adaptable Hydrogen Bond Re
Fenbendazole analog
ML
Single
Effective cytotoxic activity of OSW
Injection of an SV40 transcriptional terminator causes embryonic lethality a possible zebrafish model for screening nonhomologous end
Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple
Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease PMID 33993099
Dietary supplementation with beetroot modulates gut microbiota
Sustained induction of collagen synthesis by TGF
Epi
Ca2+
Discovery of Imidazo[1,2
Oxidation of 7
In vivo pharmacokinetics and toxicity profile of the anti
Reduced mitochondrial
Potent inhibitors of lipid droplet formation PMID 23762932
Pyridinium bisretinoid A2E
MKC
Sulfametrole 32909
Synthesis, pharmacological and antiviral activity of 1,3
T3D
Image
NTRK1
Photothermal theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient antibacterial treatment PMID 37520103
7th annual European Antibody Congress 2011 November 29
Design, synthesis and biological evaluation of 7
Prophylactic and therapeutic efficacy of mAb treatment against MERS
Microglial cells in the retina of Carassius auratus effects of optic nerve crush PMID 10701865
Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes PMID 27382187
METTL14
Centmitor
PF
Residual plasma concentrations of acitretin (Ro 10
CD164 蛋白, Human (HEK293, hFc)
Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents PMID 32403018
Nifurzide, a nitrofuran antiinfectious agent interaction with Escherichia coli cells PMID 7018391
A phase I trial of PR
BMS
The development of α, β
Hexane
Ganolucidic acid A
3
MCE
PLLA1000
Hepcidin抑制剂、基因
Boc
Antimalarial properties of floxacrine, a dihydroacridinedione derivative PMID 117747
BAY u9773, a novel antagonist of cysteinyl
Bombolitin V
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex
SLC35E1 Human Pre
Tertiapin LQ
Desferoxamine and ethyl
β
Fipronil sulfone
Inhibition of estrone sulfatase activity by estrone
Prenylated derivatives of baicalein and 3,7
Aqueous Extract of Cimicifuga dahurica Reprogramming Macrophage Polarization by Activating TLR4
A structure of human Scap bound to Insig
Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High Fat Diet During Lactation PMID 39185162
Targeted anticancer pre
Sulfaperin 599
MCE
Pharmacological inhibition of the Notch pathway enhances the efficacy of androgen deprivation therapy for prostate cancer PMID 29488214
Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation a possible role in the treatment of adenomyosis PMID 23904524
NLRP3
HLX Human Pre
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma PMID 38517048
Maslinic acid (Standard) (Crategolic acid (Standard),山楂酸 (Standard))
PROTAC Akt3 Degrader
Effects of melagatran, a new low
MCE
BTK degrader
MCE
Homogentisic acid
SMURF2 predisposes cancer cell toward ferroptosis in GPX4
Discovery of Potent and Highly Selective Interleukin
白介素 1 受体样 1(IL1RL1)基因
MPL 原癌基因,血小板生成素受体(MPL)基因
PLLA3000
Quercetin alleviates acute kidney injury by inhibiting ferroptosis PMID 33364059
Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells Role of repressing glycolysis via miR
(S)
MCE
MCE
MCE
The interaction between STAT3 and nAChRα1 interferes with nicotine
Fibulin
MCE
N
Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10 PMID 34254583
Methyl 3
The effects of autophagy on the replication of Nelson Bay orthoreovirus PMID 31319897
Design, synthesis, molecular modeling and evaluation of 2,4
Comprehensive Ocular and Systemic Pharmacokinetics of Brinzolamide in Rabbits After Intracameral, Topical, and Intravenous Administration PMID 33035542
Explore the potential mechanism of Huachansu injection against osteosarcoma via metabolomics, network pharmacology and bioinformatics PMID 40764575
Propazine 139
Preparation, characterization, assembly, and stability of walnut peptide
TTBK2 Recombinant Human Active Protein Kinase
Plantamajoside alleviates hypoxia
BI
The tubulin
Carbomer 990 (卡波姆990)
Pyrotinib promotes the antitumor effect of T
Constituents of Cannabis sativa L. XVII. A review of the natural constituents PMID 6991645
METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer
Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC
Persistent high glucose induced EPB41L4A
Bone mesenchymal stem cells promote gastric cancer progression through TGF
β
Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β
Analysis of pyrrolizidine alkaloids in Eupatorium fortunei Turcz. and their in vitro neurotoxicity PMID 33774095
Evidence for processing enzymes in the abdominal gland of the newt, Cynops pyrrhogaster, that generate sodefrin from its biosynthetic precursor PMID 17867852
Intestinal Apc
A dual absorption pathway of novel oyster
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ
Platelet changes after a saturated fat meal and their prevention by Dazmegrel, a thromboxane synthetase inhibitor PMID 3573995
NCGC00092410
The association between anti
A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non
CDKL5
Cytosine
Blocking transforming growth factor
Monoclonal Antibodies for Prevention of Respiratory Syncytial Virus Infection PMID 34042909
L
Cheminformatic Read
Determination of Metabolic Viability and Cell Mass Using a Tandem Resazurin/Sulforhodamine B Assay PMID 27145111
Acetazolamide 59
JNJ
Pharmacological activities of droloxifene isomers PMID 3218958
Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8
Controlled release of stromal cell
Tubulysin M
Fibrinogen/AKT/Microfilament Axis Promotes Colitis by Enhancing Vascular Permeability PMID 33075564
Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2 PMID 39885145
Nonanoyl
Tubulin polymerization
Prenatal dexamethasone exposure reduces osteoprogenitor proliferation in mice via histone modifications at the Mkp
BRD4 Inhibitor
SST4
Chondroitinase ABC (ChABC,软骨素酶ABC)
Antihyperglycemic effect of dehydroepiandrosterone analogue 16 alpha
Both endoplasmic reticulum and mitochondria are involved in disc cell apoptosis and intervertebral disc degeneration in rats PMID 19960285
Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4
N6
Adipose
N
Neuromedin B (神经介素 B)
Bimatoprost cyclohexyl amide (N
BVT.2733, a selective 11β
IL33
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β
Intestinal mucosal barrier repair and immune regulation with an AI
Recurrent hotspot mutations in HRAS Q61 and PI3K
HAECs
Androgen induces 3'UTR shortening of de novo lipogenesis genes by alternative polyadenylation in prostate cancer cells PMID 40643802
Prostaglandin K2 (PGK2)
Sulfo
CAMKK2 restored mitochondrial dynamics homeostasis to alleviate pulmonary fibrosis via AMPK/PGC
Antimitotic and cytotoxic activities of guattegaumerine, a bisbenzylisoquinoline alkaloid PMID 3575505
MD2 deficiency prevents high
2
Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone
Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin
Biosynthesis of antitumor antibiotic, cytogenin PMID 8195044
Design, synthesis, antiproliferative activity, molecular docking and cell cycle analysis of some novel (morpholinosulfonyl) isatins with potential EGFR inhibitory activity PMID 30096580
A substituted tetrahydro
Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction PMID 27852045
MCE
Cleistanthin B (Diphyllin O
BI
27153
STAMBP
Consolidating Organometallic Complex Ir
Guacetisal 55482
1,2,3,6,7,8
Sturgeon (Acipenser schrenckii) spinal cord peptides Antioxidative and acetylcholinesterase inhibitory efficacy and mechanisms PMID 39153375
Activity
Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA
PCMX
The adhesion G
Tetrabutylammonium perchlorate 1923
3,4
SYTO
Coriatin 91653
α
Mafenide acetate in burn treatment PMID 5576444
MLS
Effect of 2
Design, synthesis, and biological evaluation of novel amidoxime or amidine analogues of some 4
GSTs
GPI
Isocucurbitacin B inhibits glioma growth through PI3K/AKT pathways and increases glioma sensitivity to TMZ by inhibiting hsa
Human placenta mesenchymal stromal cells alleviate intestinal inflammation and repair intestinal barrier function by activating AMPK
Bufexamac 2438
release
Lomefloxacin Induces Oxidative Stress and Apoptosis in COLO829 Melanoma Cells PMID 29053584
Canagliflozin synergises with serine restriction mediating anti
T
Bis(m
(S)
JQ1, a bromodomain inhibitor, suppresses Th17 effectors by blocking p300
Leucomyosuppressin
Afatinib impurity 5 402855
Human apolipoprotein B (人载脂蛋白B)
t
Bioactive carbazole alkaloids from Clausena wallichii roots PMID 22482432
Zidesamtinib Selective Targeting of Diverse ROS1 Drug
ONO
Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells PMID 21961726
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling PMID 40084691
MCE
DSPE
AZD
Vasopressin
Dihydrofolate reductase (DHFR)降解剂、基因
16
Alkaloids from Oxytropis ochrocephala and antiproliferative activity of sophoridine derivatives against cancer cell lines PMID 26865176
Ultracentrifugation studies of the location of the site involved in the interaction of pig heart lactate dehydrogenase with acidic phospholipids at low pH. A comparison with the muscle form of the enzyme PMID 17334683
Quercetin targets the Ccl4
Lapaquistat 189059
Methyl 2
A MYC
STE
PROTAC SMARCA2 degrader
KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy PMID 34059001
Silibinin attenuated pseudo
MCE
EIF3A Human Pre
The CD146
Urinary excretion of 2,3
Primulic acid I (Primulasaponin 1)
Dilazep potentiation of adenosine
Multi
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation PMID 36347997
肌球蛋白磷酸酶 Rho 相互作用蛋白(MPRIP)基因
Bioassay
Cela2a
Exploring the mechanism of Lianhuaqingwen (LHQW) in treating chronic bronchitis based on network pharmacology and experimental validation PMID 39095732
Inhibitory effects of (2S, 3S)
fluorescence
Synthesis and biological evaluation of a new vitamin D2 analogue PMID 22926068
[DAla2, DArg6] Dynorphin A, (1
Anti
Environmental enrichment combined with fasudil promotes motor function recovery and axonal regeneration after stroke PMID 33907042
PINK1/Parkin
Exploring Degradation of Mutant and Wild
Erythrabyssin II 77263
MCE
Nuclear translocation of ISG15 regulated by PPP2R2B inhibits cisplatin resistance of bladder cancer PMID 38976080
Effects of new
Diclofop 40843
m
BPZ inhibits early mouse embryonic development by disrupting maternal
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B
MCE
Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation PMID 30896884
Latanoprost acid
FGFR1 inhibitor
FGFR
MCE
Optical magnetic multimodality imaging of plectin
S
4
Hydrocortisone buteprate 72590
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