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Cys
Urinary Organic Acids Increase After Clinical Stabilization of Hospitalized Children With Severe Acute Malnutrition PMID 31303023
CUDC
Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma
L
L
CRBN ligand
Silybin A 22888
Cyanidin 13306
Methyl 8
TAK
LIM 结构域激酶 2（LIMK2）基因
Humanin C8A
MeV
利钠肽受体 2（NPR2）基因
Csnk2a1
Maltotriose (麦芽三糖)
SR12813 (Standard)
Brevinin
LSD1
NocII
Design and Biophysical Characterization of Second
3
GPR84 antagonist 10
Electropolymerized MIP with MWCNTs on Stir Bar Using Multivariate Optimization for Tetradifon Detection in Date PMID 31549598
Homo Sildenafil 642928
Dimethyldioctadecylammonium
S
Stearidonic acid 20290
CRD
Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics PMID 31467181
Pratensein ameliorates β
SIRT2
2
UU
Neuroprotective efficacy of caramiphen against soman and mechanisms of its action PMID 21486285
D
The pharmacology of iprindole, a new antidepressant PMID 4390823
Heneicomycin, a new antibiotic (A21A) fermentation, isolation, and antibacterial spectrum PMID 468741
Preparation of VX765 sodium alginate nanogels and evaluation of their therapeutic effect via local injection on myocardial infarction in rats PMID 38475920
Further observations on the folate
Stearidonic acid, an inhibitor of the 5
MCE
Lapiteronel 1260006
Pax9 Mouse Pre
CRBN ligand
TL1A/TNFSF15 蛋白, Rat (HEK293, Fc)
Gageotetrins A
Martynoside 67884
BAPTA tetrapotassium 73630
Alisertib shows negligible potential for perpetrating pharmacokinetic drug
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity PMID 37291955
TPEN 16858
GEM 231, a second
KSI
Effects of N2,N2
CRELD2 Human Pre
Neuroprotective effect of 6
New indolylarylsulfones as highly potent and broad spectrum HIV
降解剂
Viologen dendrimers as antiviral agents the effect of charge number and distance PMID 20377249
ARMET/MANF 蛋白, Human (HEK293, His)
autoimmune encephalomyelitis
Cenderitide a multivalent designer
Strictosamide and mitraphylline inhibit cancer cell motility by suppressing epithelial
(18α)
Pirprofen (SU 21524)
zyg
Role of caftaric acid in lead
TRAP 抗体 (YA5741)（TRAP Antibody (YA5741)）
Effect of α
Cul2 Rat Pre
Bicinchoninic acid 1245
Armillaramide 111149
Induction of apoptosis and caspase
Choline oxidase, Arthrobacter globiformis
光药大黄花提取物 (Cymbaria mongolica Maxim.)
Diterpenes from a Chinese collection of the brown alga Dictyota plectens PMID 25495797
Epidermal growth factor induces WISP
The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production PMID 18786164
Further Exploring Solvent
Syringetin
Rosmarinyl glucoside 910028
Nephthenol 53915
Ombuoside from Gynostemma pentaphyllum Protects PC12 Cells from L
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus
Development and preclinical studies of broad
BRAP Human Pre
Fermentation product butane 2,3
Development and validation of a new HPTLC
Clinical studies in patients with solid tumors using a second
HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma PMID 28028031
RS 8359 105365
Near infrared readouts offer sensitive and rapid assessments of intestinal permeability and disease severity in inflammatory bowel disease models PMID 32170183
Diclofenac diethylamine 78213
NR
Quinolone alkaloids with antibacterial and cytotoxic activities from the fruits of Evodia rutaecarpa PMID 23651559
胰腺导管腺癌 (Pancreatic Ductal Adenocarcinoma)
Detection of peptidases in Trypanosoma cruzi epimastigotes using chromogenic and fluorogenic substrates PMID 1594295
粉背薯蓣提取物 (Dioscorea collettii var. hypoglauca (Palib.) C. Pei & C. T. Ting)
M1002
Prodigiosin 82
Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients PMID 28985181
Effect of s
Bis(2R,3R)
Characterization of U
Selective inhibition of fibroblast activation protein protease based on dipeptide substrate specificity PMID 16410248
S100A1 蛋白, Human (His)
Initiation and processing of signals from the B cell antigen receptor PMID 9143696
Sym021, a promising anti
Bonducellin
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure
SYD985, a Novel Duocarmycin
Syntheses of aminoalcohol
ACS
Acridine Orange zinc chloride salt 10127
NADH oxidase 9032
The Binding Mode of the Sonic Hedgehog Inhibitor Robotnikinin, a Combined Docking and QM/MM MD Study PMID 29109946
EPZ
CRBN ligand
Metabolism of methocarbamol in the rat, dog, and human PMID 5548215
Chd1l
Excitotoxic neuroprotection and vulnerability with CaMKII inhibition PMID 21316454
Glutaminase 抗体 (YA406)（Glutaminase Antibody (YA406)）
CRBN ligand
The promoting effect of the POU3F2/METTL16/PFKM cascade on glycolysis and tumorigenesis of hepatocellular carcinoma PMID 39756795
ADAM17
CID 697851
Identification of the phytosphingosine metabolic pathway leading to odd
Jaboticabin and Related Polyphenols from Jaboticaba ( Myrciaria cauliflora) with Anti
Synthesis and anti
Adgre5 Rat Pre
Enzymatic activity of fibroblast activation protein
Anti
Evaluation of in vivo antitumor activity of cleistanthin B in Swiss albino mice PMID 27774423
Targeting MAT2A synergistically induces DNA damage in osteosarcoma cells through EZH2
L
Multimodal profiling of proinflammatory protease activity identifies caspase
Boc
Synthesis and anti
VISA
1
Ledol 577
Synthesis and evaluation of new 2
Trypsin, elastase, plasmin and MMP
N
Novel pyridinone derivatives as non
CRBN ligand
The effects of CEP
MCE
H4C2 Human Pre
CRBN ligand
25
The role of the calpain
Pax9 Rat Pre
CRBN ligand
A novel family of diarylpyrimidines (DAPYs) featuring a diatomic linker Design, synthesis and anti
Chemotaxis
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome PMID 35422502
β
Ophiopogonin C 65586
Nectandrin B 74683
Quinine pharmacokinetics and toxicity in cerebral and uncomplicated Falciparum malaria PMID 6751085
MCE
Tonapofylline 340021
Inhibition of tubulin polymerization by select alkenyldiarylmethanes PMID 18083556
CRBN ligand
CRBN ligand
Condurango glycoside A0 115810
Polygalic acid 1260
Metoclopramide
Brentuximab Vedotin in the Treatment of Peripheral T Cell Lymphoma and Cutaneous T Cell Lymphoma PMID 32016790
Exploiting the hydrophobic channel of the NNIBP Discovery of novel diarylpyrimidines as HIV
CRBN ligand
CRBN ligand
Repurposing human kinase inhibitors to create an antibiotic active against drug
Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL
Design, Synthesis, and Evaluation of Thiophene[3,2
19
Antiviral effect of antileukemic drugs N4
TAS
Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway PMID 31078398
Thiophene
Ac
CRBN ligand
Me
Engeletin 572
PROTAC BCL6 Degrader
CRBN ligand
Distinct Signaling Patterns of Allosteric Antagonism at the P2Y1 Receptor PMID 28864555
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G
F8 Rat Pre
CRBN ligand
Pharmacophore
MGAM Human Pre
Activity and molecular modeling of a new small molecule active against NNRTI
seryl
N
Guanabenz hydrochloride 23113
Orf 17910 87107
MCE
Antioxidant and cyclooxygenase activities of fatty acids found in food PMID 11929276
ADGRE5 Human Pre
Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration PMID 10344662
Triethylphenylammonium iodide 1010
MCE
Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells PMID 29088802
MCE
Mal
mTOR signaling promotes rapid m6A mRNA methylation to regulate NK
HPK1 ligand 6
A photoactivatable antibody
CRBN ligand
An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression PMID 10082234
Lodinixil
Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection PMID 36717839
酪蛋白激酶 2 α 1（CSNK2A1）基因
Creld2 Rat Pre
Diarylpyrimidine
Discovery of novel 2
FMRF
SMC4 Human Pre
MCE
Brap Mouse Pre
The Biology of Retinoblastoma PMID 26310174
Mogroside II B (罗汉果苷II B)
Induction of novel agonist selectivity for the ADP
Exploring the role of 2
CRBN ligand
NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity PMID 23904161
MCE
Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV
Antibacterial activity of lichen secondary metabolite usnic acid is primarily caused by inhibition of RNA and DNA synthesis PMID 24571086
RTN4R Human Pre
Ganglioside GM3 inhibits the high glucose
MCE
Isozyme selective inhibition of cGMP
Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS PMID 15264227
On the Road towards Small
Mechanisms of 5
Fused heterocycles bearing bridgehead nitrogen as potent HIV
The oncogenic role of SPOCK1 in lung carcinoma by promoting immune evasion and its related mechanisms PMID 40626151
CRBN ligand
L
CD24hiCD27+ Bregs within Metastatic Lymph Nodes Promote Multidrug Resistance in Breast Cancer PMID 37831062
Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis a 6
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure
肿瘤微环境
CAB39 抗体 (YA2761)（CAB39 Antibody (YA2761)）
CD137/4
PIAS2 Human Pre
Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer PMID 39123442
Gy
erythro
Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells PMID 27098859
3,4
Discovery of potent antiosteoporotic cyclic depsipeptides with an unusual nitrile hydroxy acid from Microascus croci PMID 39798453
CRBN ligand
CRBN ligand
S100A1 蛋白, Human (HEK293, hFc)
Tau Peptide (294
Discovery of novel indolylarylsulfones as potent HIV
刚果臂形草提取物 (Brachiaria ruziziensis Germ. & Evrard)
岩玫瑰提取物 (Talinum calycinum Engelm. in Wisl.)
Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis PMID 27006447
Somatostatin Receptor 2 抗体 (YA3946)（Somatostatin Receptor 2 Antibody (YA3946)）
Vsx2 Rat Pre
CRBN ligand
Sdc4
Indantadol 202844
Nucleolin 抗体 (YA6194)（Nucleolin Antibody (YA6194)）
CRBN ligand
A comparison of Ro 16
Flexible 2,4
CRBN ligand
Repurposed AT9283 triggers anti
5
Novel 2
CRBN ligand
Interleukin 8 (CXCL8)
10
Phleomycin E
Flurithromycin ((8S)
Anticancer agent 35
BCX
Famprofazone (芳香法宗)
Kiss2 peptide 1111070
Taloxin ((S)
Radotinib inhibits multiple myeloma cell proliferation via suppression of STAT3 signaling PMID 35503759
Nebidrazine 55248
AZD
Col4a3
Metuzumab (Licartin)
Dab2
(S)
Propargyl
Pharmacological and behavioral profile of N
An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering PMID 37131705
9(S)
CRBN ligand
(S)
Rosmanol 80225
CRBN ligand
CRBN ligand
INK4C
RH
Pirazolac (ZK
Paroxypropione (4'
ERB
Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF
MurF
S62798
AZ513
Kebuzone (Ketazone)
血管生成素（ANG）基因
N
NIBR
Hyls1 Rat Pre
LG
3′
(4
Bephenium 7181
M
TAMRA
Phoenistatin
ΔDi6S
Nor
Chronic Psychological Stress Attenuates the Efficacy of anti
Antitumor agent
Anti
Alcohol Oxidase, Pichia pastoris
FR
AZD
N
L
GZD
Design, synthesis and anti
mrs 4062 TFA
磷酸二酯酶 3B（PDE3B）基因
Myosin Regulatory Light Chain MRCL3 (11
染色质结构域解旋酶 DNA 结合蛋白 1 样（CHD1L）基因
COX
4N1K peptide
Citryl
MCE
PH 结构域和富亮氨酸的重复蛋白磷酸酶 1（PHLPP1）基因
Nephrotoxic effect of tetradifon in rats a biochemical and histomorphometric study PMID 21216578
Pias2 Mouse Pre
硒磷酸合成酶 1（SEPHS1）基因
Neosordarin
肌苷一磷酸脱氢酶 1（IMPDH1）基因
Vitamin C enhances the in vitro development of early porcine embryos by improving mitochondrial function PMID 39306701
IDO1
Design and synthesis of N₁
Dermaseptin
Discovery and pharmacological characterization of N
Ube2n
MCE
APBB2 Human Pre
远端膜臂组件组件 1（DMAC1）基因
富脯氨酸的蛋白质 BstNI 亚家族 1（PRB1）基因
Celesticetin
Discovery of a novel class of highly potent, selective, ATP
Prophylactic Effect of BIO
Rilpivirine 500287
Indolylarylsulfones as HIV
Differentiating agents in the treatment of leukemia PMID 2201823
MptpB
Benastatin B
5
FKGK18
(Z)
Losmiprofen (氯米洛芬)
Fibrostatin A
Ethamoxytriphetol (MER
DNA 损伤诱导转录物 4（DDIT4）基因
Phosphatidylcholine, PC (heart, bovine)
S 1924
10(S)
Application of structure
Design and synthesis of 2
Fmoc
Ccdc134
Diosbulbin I 1187951
TRAP 抗体 (YA5670)（TRAP Antibody (YA5670)）
ML278
MDL
3
Medrogestone (美屈孕酮)
Tripropionin (Glycerol tripropionate，三丙酸甘油酯)
VLX1570
Piroctone
N
S100A1 蛋白, Human
APLN Human Pre
MK
Discovery of VU6025733 (AG06827) A Highly Selective, Orally Bioavailable, and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy PMID 41581069
Design, synthesis, and actions of a novel chimeric natriuretic peptide CD
MCE
2
Biotransformation of nevirapine, a non
ABT
嗅觉调节素 4（OLFM4）基因
Cytochalasins block actin filament elongation by binding to high affinity sites associated with F
Synthalin A sulfate
Radotinib Decreases Prion Propagation and Prolongs Survival Times in Models of Prion Disease PMID 37569615
16 1 (DELTA 9
AMA
间变性淋巴瘤激酶（Alk）基因
5
JK
PBRM1/SMARCA2,4
Design, synthesis, and biological evaluation of 1
白细胞介素 12 a（Il12a）基因
PHD2
Antitumor studies. Part 4 Design, synthesis, antitumor activity, and molecular docking study of novel 2
Tk2 Rat Pre
MCE
International Union of Pharmacology. LXIV. Estrogen receptors PMID 17132854
Nonadecanoyl
Discovery of uracil
Anti
Etodolac acyl glucuronide
MCE
Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases PMID 10473566
CRBN ligand
CRTC1 enhances PD
Generation of HepG2 Cells with High Expression of Multiple Drug
Isoginkgetin 548
Uncoupling melanogenesis from proliferation in epidermal melanocytes responding to stimulation with psoriasis
CRBN ligand
MRPL12 Human Pre
trans
Downregulation of tyrosinase activity in human melanocyte cell cultures by yohimbine PMID 10651985
G6PC2 Human Pre
Kebuzone (Standard)
Discovery and Structure
PWP1 抗体 (YA1784)（PWP1 Antibody (YA1784)）
1,2
FAK
Inhibitory effect of trans
The D
Aryl Substituted Benzimidazolones as Potent HIV
Columbianadin attenuates doxorubicin
The miR
LCORL Human Pre
Starfish
HYLS1 Human Pre
8
Novel N1
Synergistic inhibition of HIV
Serotonin
Molecular composition of IMP1 ribonucleoprotein granules PMID 17289661
TNRC6C Human Pre
ZNF468 inhibits irradiation
PAX9 Human Pre
Boc
Robust proteome profiling of cysteine
Normal cone function requires the interphotoreceptor retinoid binding protein PMID 19357286
Classic histamine H1 receptor antagonists a critical review of their metabolic and pharmacokinetic fate from a bird's eye view PMID 12678691
6
SEC61A 抗体 (YA1825)（SEC61A Antibody (YA1825)）
Separation of detoxin complex and characterization of two active principles, detoxin C1 and D1 PMID 5726294
3,4
Mga Mouse Pre
MCE
Feruloyl
MCE
Methyl 4
程序性细胞死亡
Discovery of the investigational drug TAK
Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV
Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features PMID 29556353
20β
过量 4（SURF4）基因
Small
Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic A Randomised, Single
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor PMID 36371441
PODXL Human Pre
Discovery of 6
FIP1L1 Human Pre
Leucine dehydrogenase, Bacillus sp.
CRBN ligand
CRBN ligand
Substance P (7
EP2
CO
Mollugin enhances the osteogenic action of BMP
7
Tricarbonyldichlororuthenium(II) dimer, the lipid
cis
Apoptosis of human T
Characterization of Alisertib (MLN8237), an investigational small
5
Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells PMID 31282672
Synthesis and anti
Effects of thiocyanate and AMPA receptor ligands on (S)
Liquid
SHP2
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