最近收录_第610页_生物活性分子
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Tight junction proteins at the blood
富丝氨酸和精氨酸的剪接因子 9（SRSF9）基因
Biocatalyst
MCE
(±)
H
L858R/T790M
NEP28
L
2
MCE
MCE
MCE
MCE
Hedonal 541
MCE
Bsg Rat Pre
Calml5 Rat Pre
MCE
DL
MCE
MCE
(S)
MCE
MCE
BID Human Pre
RGDT 93675
SARS
Pfdn5 Rat Pre
HMGXB4 Human Pre
Azlocillin can be the potential drug candidate against drug
IX
6
MCE
Anti
Lifespan
C 型凝集素结构域家族 4 成员 M（CLEC4M）基因
MYO3B promotes cancer progression in endometrial cancer by mediating the calcium ion
Clemastine attenuates subarachnoid haemorrhage pathology in a mouse model via Nrf2/SQSTM1
Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma PMID 28656278
DL
Endoplasmic reticulum stress promotes blood
MCE
Pmch Rat Pre
sn
7
类固醇受体 RNA 激活因子 1（SRA1）基因
EDNRB Human Pre
缺铁性贫血 (Iron Deficiency Anemia)
CD24 蛋白, Human (HEK293, Fc)
Linolenyl alcohol (Standard)
MCE
Chloroprocaine (2
APRIL/TNFSF13 Trimer 蛋白, Human (HEK293, His
MCE
EGFR influences the resistance to targeted therapy in BRAF V600E melanomas by regulating the ferroptosis process PMID 40024937
TRPA1 Antagonist 1 1984825
Boc
Kdm4c Rat Pre
Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD
Famoxadone (DPX
Anthopleurin
Biodegradation of the acetanilide herbicides alachlor, metolachlor, and propachlor PMID 9561822
The mechanism of HMGB1 secretion and release PMID 35217834
Quinidine
Selenium Ameliorates Acetaminophen
MCE
Pancreatic islet
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress PMID 19789631
DNA
2
Coriolin A 33404
Bavachin induces apoptosis in colorectal cancer cells through Gadd45a via the MAPK signaling pathway PMID 36641231
MCE
MCE
Phosphatidylinositol bis
MCE
Glucagon
Polysaccharide enhanced NK cell cytotoxicity against pancreatic cancer via TLR4/MAPKs/NF
MCE
MCE
L 722151 122841
Synthesis and biological evaluation of novel aromatic
Tanshinone IIA Activates Nuclear Factor
Z57346765
MCE
METTL3 suppressing SLC31A1 m6A modification regulates trophoblast migration and invasion PMID 40088504
载脂蛋白 D（APOD）基因
Pridefine 5370
N
HLA
MCE
多巴胺 β 羟化酶（Dbh）基因
Albumin
Patrinoside aglucone (Patrinoside aglycone)
MCE
Cyclopentolate 512
Angiotensinogen (1
MCE
MCE
MCE
MCE
Small
MCE
混合谱系白血病蛋白 1
Orobol 480
MCE
4
MCE
MCE
Atp1a2 Rat Pre
Atp1b2 Mouse Pre
Regiospecific and enantioselective metabolism of 8,9
锌指蛋白 263（ZNF263）基因
MCE
MCE
CLK3 Human Pre
Roxindole psychopharmacological profile of a dopamine D2 autoreceptor agonist PMID 8558454
Lactitol 585
Discovery of Novel, Selective, and Nonbasic Agonists for the Kappa
Adrb1
Structure
E2508
脂酰转移酶 1（LIPT1）基因
Epirosmanol 93380
MCE
Influence of Small Molecular Property on Antibody Response PMID 32854496
11007
MCE
MCE
Zymosterone 27192
Amino
MCE
HCV
MCE
Z
DX
Bardoxolone methyl modulates efflux transporter and detoxifying enzyme expression in cisplatin
MCE
5'
LaKe
PTH1R agonist 4
serpin 家族 H 成员 1（SERPINH1）基因
serpin 家族 B 成员 3（SERPINB3）基因
KR
MCE
MCE
MRE
MCE
Erysenegalensein E (伊里塞加菌素 E)
Dot1L
MCE
MCE
ACYP2 functions as an innovative nano
Dermenkephalin (Tyr
NFE2L2 protects against Sorafenib
Selective Chemical Inhibition of PGC
A short
Exploiting structural variability in the kinase back
Magnesium isoglycyrrhizinate ameliorates high fructose
Apigenin 6,8
Chm
MCF
MCE
Anapc1 Rat Pre
MCE
MCE
MCE
EFNA3 Human Pre
LWG
Beclomethasone 17
MCE
线粒体转录终止因子 3（MTERF3）基因
Protein phosphatase 6 (Pp6) is crucial for regulatory T cell function and stability in autoimmunity PMID 35224167
Lidocaine methiodide (Methyllidocaine iodide)
Optimized low
Human apolipoprotein CIII (人载脂蛋白CIII)
4
(R)
m
The Role of the AMPK Pathway in ZEA
Anti
MCE
Glycyl
MCE
MBCQ 150450
3
NEDD9 sustains hexokinase expression to promote glycolysis PMID 35410460
Liposomal L
MD1 deletion exaggerates cardiomyocyte autophagy induced by heart failure with preserved ejection fraction through ROS/MAPK signalling pathway PMID 32648659
Anti
Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation PMID 33256189
Discovery of SARS
HDAC2 promotes colorectal tumorigenesis by triggering dysregulation of lipid metabolism through YAP1 PMID 39875048
Naptumomab estafenatox a new immunoconjugate PMID 20053143
PBT 1033 (Standard) (PBT 2 (Standard))
(S,E)
SOCS1 acts as a ferroptosis driver to inhibit the progression and chemotherapy resistance of triple
An inhibitory effect of schisandrone on α
N
PLLA4000
The moonlighting function of glycolytic enzyme enolase
FR900098 66508
SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation PMID 36918544
Tyrosinase
N
Zinc sulfate monohydrate
Fmoc
Paxillin 抗体 (YA243)（Paxillin Antibody (YA243)）
A new method for evaluating sigma(2) ligand activity in the isolated guinea
SMARCB1 Promotes Ubiquitination and Degradation of NR4A3 via Direct Interaction Driven by ROS in Vascular Endothelial Cell Injury PMID 33163142
Estrogen receptor beta signaling enhances extinction memory recall for heroin
Inhibition of Pim kinases triggers a broad antiviral activity by affecting innate immunity and via the PI3K
Identification of a possible secondary picrotoxin
The effects of different potato dextrose agar media on secondary metabolite production in Fusarium PMID 33872940
Valeryl Bromide 1889
Discovery of Selective PDE1 Inhibitors Alleviating Pulmonary Fibrosis by the Regulation of TGF
Design and characterization of N
(20R)
BW A575C, a chemically novel agent with angiotensin converting enzyme inhibitor and beta
3,4
Protective effects of hypericin against infectious bronchitis virus induced apoptosis and reactive oxygen species in chicken embryo kidney cells PMID 31399732
Venturicidin A, A Membrane
Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation PMID 32123161
肌营养蛋白γ2（SNTG2）基因
Azobenzene
N
Phenylglyoxylic acid
MCE
HLA
Sulfo
MCE
XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathway PMID 32377720
MCE
MCE
ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A
Reversible inhibition of acetylcholinesterase by eseroline, an opioid agonist structurally related to physostigmine (eserine) and morphine PMID 7092918
MCE
2
MCE
MCE
MCE
Discovery and SAR exploration of novel nanomolar 3,4
Falcarindiol Suppresses Malignant Progression and Induces Ferroptosis in Non
MCE
MCE
Elaidyl
硫酸羟基氯喹
MCE
Compound Z526 alleviates chemotherapy
N
Deep learning
MCE
Ononin alleviates endoplasmic reticulum stress in doxorubicin
3,5
Cimetidine sulfoxide 54237
Disperse orange A 6657
Poacic acid 160097
Rc3h2
TROP
Human apolipoprotein AIV (人载脂蛋白AIV)
Nortanshinone
Preventing respiratory syncytial virus (RSV) disease in children PMID 33986169
Normal aortoiliac diameters by CT PMID 3392259
MCE
Dot1L
N
Near
MCE
cGAS
TFAX 568, SE (AFDye 568 NHS Ester)
Verapamil in arrhythmia PMID 3530300
MCE
9(E),11(E)
GLS2 Human Pre
Oxybuprocaine 99
4
D
MCE
MCE
Sftpc Mouse Pre
PTH1R agonist 2
(Rac)
Tyrosine analogues as alternative substrates for protein tyrosine kinase Csk insights into substrate selectivity and catalytic mechanism PMID 10896106
Valsartan
6
C
Enhanced dissipation of xenobiotic agrochemicals harnessing soil microbiome in the tillage
IIIM
Novel celastrol derivatives with improved selectivity and enhanced antitumour activity Design, synthesis and biological evaluation PMID 28688281
2
LF 1695 86187
m
IRAK4 ligand
Menin‑MLL inhibitors induce ferroptosis and enhance the anti‑proliferative activity of auranofin in several types of cancer cells PMID 32945449
Annexin
MI
Parvodicin B2 110882
β
CKAP4 in hepatocellular carcinoma competitive RETREG1/FAM134B binding, reticulophagy regulation, and cancer progression PMID 39689859
Functionalized regioisomers of the natural product phenazines myxin and iodinin as potent inhibitors of Mycobacterium tuberculosis and human acute myeloid leukemia cells PMID 39788066
β2
Screening for inhibitors of the SOD1 gene promoter pyrimethamine does not reduce SOD1 levels in cell and animal models PMID 20638444
Cytosporin B
MCE
1,5,8
Dihydroobovatin (二氢倒卵灰毛豆素)
MCE
TDI
Synthesis and pharmacological characterization of 2
Experimental investigation and observations on the diuretic action of quinethazone PMID 6012607
Valproic acid impurity 1 (Standard)
5
Lyn
Ethotoin 86
Blocking tumor
Chip
Clk3 Mouse Pre
Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis PMID 33872697
MCE
Online Charge
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF
CDK18/CycY Recombinant Human Active Protein Kinase
Cefoxazole 36920
LPS
Semastatin 5A.2 929555
食管癌
MCE
MCE
Discovery, structure
Function and mutual interaction of BiP
TYRO3 蛋白酪氨酸激酶（TYRO3）基因
真核翻译起始因子 4E
Laquinimod, an up
Hibarimicin C
E74 样 ETS 转录因子 1（ELF1）基因
Sodium 6
Toxicity studies with ethyl maltol PMID 5353824
Methyl 2,5
MCE
GSK2983559
PK9327 2413987
MCE
Sorafenib 284461
Inverse heavy
MCE
MIA 蛋白, Human (His)
Human immunodeficiency virus type 1 (HIV
ST2/IL1RL1 蛋白, Human (HEK293, His)
Cib1 Rat Pre
MCE
S100A9 蛋白, Mouse (His)
ST2/IL1RL1 蛋白, Human (HEK293, Fc)
MCE
Ticagrelor impurity 5
MCE
泛素特异性肽酶 11（USP11）基因
MCE
Menthol derivative WS
细胞质 FMR1 相互作用蛋白 1（CYFIP1）基因
Betamethasone dipropionate 5593
Correlation of antiangiogenic and antitumor efficacy of N
α
Islandicin 476
Antibody microarray
MCE
MCE
Efna3 Mouse Pre
BAFF/TNFSF13B 蛋白, Human (His
Phospholipase C delta 1 inhibits WNT/β
Design, synthesis, and biological evaluation of novel N
Coronavirus S protein
MCE
Discovery of novel p
Design and Characterization of the First Selective and Potent Mechanism
MCE
Novel mechanism of cardiac protection by valsartan synergetic roles of TGF
MCE
SLC6A19
Ednrb Rat Pre
MCE
Iodomethane
ZC9
MCE
m
GET3 Human Pre
MCE
MCE
MCE
MCE
Pld1
MRS4620
LLW
BDW568
Tris Dodecyl Sulfate 50996
1,8
MCE
3
Stearyl arachidate 22432
Avermectin B1a aglycon 71828
Epha4
MCE
Identification of 3 beta
MCE
Determination of (15R)
Vitamin D increases glucocorticoid efficacy via inhibition of mTORC1 in experimental models of multiple sclerosis PMID 31030237
SB 242084 monohydrochloride
Synthesis of dolutegravir derivatives modified by 1,2,3
Ongoing progress in BRAF
Compounds that target host cell proteins prevent varicella
The activation of cGAS
Antithrombotic effect of PMC, a potent alpha
4A
Recent advances in the development of dual VEGFR and c
Nogo
ATP1B2 Human Pre
Determination of sinapine in rapeseed pomace extract Its antioxidant and acetylcholinesterase inhibition properties PMID 30409660
Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 1,2,4
Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal inhibition of fusion and syncytia formation PMID 7678335
MCE
Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer
FMO2+ cancer
RBM39 Enhances Cholangiocarcinoma Growth Through EZH2
TZP101
Remodeling adipocytes' lipid metabolism with a polycation loaded enzyme
Tolbutamide treatment of pregnant mice repeated administration reduces fetal lethality PMID 943864
Identification of benzimidazole diamides as selective inhibitors of the nucleotide
DPPE
成纤维细胞生长因子 8（FGF8）基因
MCE
Enduracidin B 34304
Two new compounds from Glycyrrhiza glabra PMID 16087644
H
Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma PMID 40857407
GLP
Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate PMID 10694252
EphB1 recruits c
Hydrogel dressing integrating FAK inhibition and ROS scavenging for mechano
A Peptide Derived from IKK
Bromobimane probes for thiols PMID 7651193
Optimization and SAR for dual ErbB
OY
non
MCE
ONO
Nuciferine Inhibited the Differentiation and Lipid Accumulation of 3T3
MCE
MCE
VT
MCE
beta1 antagonist and beta2 agonist, celiprolol, restores the impaired endothelial dependent and independent responses and decreased TNFalpha in rat with type II diabetes PMID 17141277
Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor
MCE
In vitro stimulation of macrophages by quadrol [N,N,N',N'
P1 675123
RB 3
Aoc1
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells PMID 27048659
Two
Autocrine Interleukin
Solvent blue 97 32724
Methyl 2,5
Rotigotine impurity 1 244239
Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders PMID 31013090
ZHC
PLLA1000
o
Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation PMID 19065580
Tyr
羰基还原酶 3（CBR3）基因
1
Benzofuran
The atypical KRASQ22K mutation directs TGF
CP
IIA
Aβ42 agonist
Erucic anhydride 103213
MCE
MCE
MCE
Cbz
MCE
MCE
MCE
5
AP
Palmityl arachidate 22413
MCE
MCE
Human apolipoprotein AI, low endotoxin level (人载脂蛋白AI,低内毒)
5,6,7,8
BSG Human Pre
MCE
Berberine attenuates sunitinib
MCE
Human poliovirus receptor contributes to biliary atresia pathogenesis by exacerbating natural
MCE
Arisostatin B
PDPK1
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